Project Grant 2516603

Award Date 1/1/25
Completion Date 12/31/27
Dollars Obligated $600K
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Los Angeles, CA 90027, USA
Similar Awards
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award of $360,000 aims to uncover the intricate ways neurons communicate and how this communication influences brain development and maturation. The 5-year project, starting April 1, 2025, will utilize the model organism Caenorhabditis elegans to study the role of neuron-neuron communication, particularly through neurotransmitter-based and neuropeptidergic chemical neurotransmission, in the post-mitotic...
The National Science Foundation Division of Integrative Organismal Systems awarded $799,998 under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside. This five-year Project Grant will support research investigating the molecular mechanisms that guide neuronal migration and circuit formation in the developing cerebellum. Key products will include insights from genetic experiments using mouse models to examine the role of CRK-associated...
The National Science Foundation awarded a $138,000 Project Grant to support research titled "The Social Brain: Behavioral, Neural, and Transcriptomic Modulation of the Brain" from July 1, 2021 to June 30, 2023. This funding was provided under the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences and increase understanding of major issues facing the nation. Over the two year period of performance in Columbia, Missouri, this award will allow the...
This $550,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Georgetown University focused on understanding the dynamic regulation of the extracellular matrix and its role in maintaining synaptic stability and neural circuit function. The project aims to elucidate the mechanisms by which matrix metalloproteinases regulate the extracellular matrix to modulate neurotransmitter release and support homeostatic...
This National Science Foundation (NSF) Project Grant award to Scripps College, with a CFDA program title of "Biological Sciences", provides $340,093 to support a 5-year research project investigating the behavioral and neural mechanisms through which early-life social environments shape individual development across species. The project will use the African cichlid fish model to uncover the causal attributes of social experience that influence behavioral phenotypes via plasticity in...
This $250,000 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research by the New Jersey Institute of Technology (NJIT) to investigate the role of neuromodulators in regulating the activity and plasticity of neuronal networks. The research aims to elucidate the mechanisms by which neuromodulators constrain the parameter space of neuronal activity, both in response to perturbations and over long time scales. The project utilizes the...
This $660,000 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at the University of Southern California (USC) on how RNA editing regulates synaptic plasticity and behavioral adaptations in the fruit fly Drosophila melanogaster. The project aims to investigate how RNA editing of glutamate-gated chloride and voltage-gated calcium channels impacts neural circuit function, synaptic plasticity, and organismal behaviors....
This National Science Foundation (NSF) CAREER Program grant, awarded under the Social, Behavioral, and Economic Sciences (CFDA 47.075) program, provides $320,000 in funding to Northeastern University to investigate the neurocognitive development of adolescent learning. The project aims to understand the cognitive and brain mechanisms related to learning from experience and how these change from childhood through adolescence and young adulthood. Using behavioral, computational, and neuroimaging...
This National Science Foundation (NSF) Project Grant award under the Social, Behavioral, and Economic Sciences (CFDA 47.075) program provides $466,640 to The Trustees of Princeton University to measure how visual space is represented in the parietal and cerebellar cortex, and how this representation matures from childhood to adulthood. The goal is to understand how these developing brain structures support a child's improving ability to control attention across visual space during tasks like...
This $495,341 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research at Smith College to investigate the G protein-coupled receptor GPR37 and its role in regulating the maturation of new neurons in the adult hippocampus. The project aims to build on preliminary findings that suggest GPR37 may potentiate Wnt signaling to positively influence the integration of newborn neurons into established brain circuits. Key aspects of...

This National Science Foundation (NSF) Project Grant award under the Biological Sciences (CFDA 47.074) program provides $600,000 in funding to Children's Hospital Los Angeles (CHLA) to investigate the mechanisms by which receptor tyrosine kinases regulate brain circuit development and complex behaviors. The research aims to determine the impact of dysregulating receptor tyrosine kinase function on the maturation of brain circuits controlling social and emotional behaviors. Key objectives include measuring the effects of altered receptor phosphorylation on dendritic growth, synaptogenesis, and neuron activity in the developing cortex. The multi-year award, running from January 2025 to December 2027, represents a new collaboration between researchers in the U.S. and Switzerland to advance the understanding of fundamental neurodevelopmental processes underlying complex behaviors across species.

Generated 6/10/25, 5:44 AM