The National Science Foundation Division of Integrative Organismal Systems awarded $799,998 under the Biological Sciences program (CFDA 47.074) to the Regents of the University of California at Riverside. This five-year Project Grant will support research investigating the molecular mechanisms that guide neuronal migration and circuit formation in the developing cerebellum. Key products will include insights from genetic experiments using mouse models to examine the role of CRK-associated substrate adapter proteins in cerebellar development and lamination. The grant aims to advance understanding of neuronal circuit development and potential causes of neurodevelopmental disorders by exploring how these proteins help neurons and glial cells interpret signals during migration through the cerebellum. Outreach and education efforts are also included to promote STEM career exposure for high school and undergraduate students through hands-on research experiences in neural development.
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