Project Grant 2516508
- This Project Grant award, titled "EAGER: TRTECH-PGR: LEVERAGING DNA ADP-RIBOSYLATION FOR GENE EDITING IN PLANTS", is funded by the National Science Foundation's Biological Sciences program (CFDA 47.074) in the amount of $299,932. The award was made on July 15, 2025 with a target completion date of June 30, 2027. The primary objectives of this project are to improve the efficiency of a recently developed bacterial genome editing tool in two model plant species, tobacco and...
- The National Science Foundation awarded a $300,000 EAGER grant titled "ENHANCING PLANT IMMUNITY AND GROWTH WITH CELL-PENETRATING PEPTIDES FOR ORGANIC AGRICULTURE" to The Ohio State University under the agency's Biological Sciences (CFDA 47.074) program. This two-year project aims to improve the efficiency of plant biologics, such as defense activators and biostimulants, by leveraging membrane translocation domain (MTD) technology to enhance their cellular delivery and efficacy. Key...
- This $234,063 National Science Foundation (NSF) project grant, awarded under the NSF Engineering program (CFDA 47.041), seeks to engineer plants to produce enhanced therapeutic proteins and improve protein production performance. The key objectives are to: 1) investigate the glycosylation and functions of glycosyl-phosphatidyl-inositol (GPI)-anchored proteins (GPI-APs) engineered in plant cells; 2) assess the broader applicability and potential applications of GPI-APs in plant cells; and 3)...
- This Project Grant award, funded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), aims to develop new biotechnology for accelerating crop improvement through an intragenic genome engineering approach. The research seeks to adjust, combine, and transfer desired DNA elements sourced from the same plant species to improve crop traits such as grain yield and disease resistance, which can be adopted faster than traditional transgenic crop development approaches. The...
- This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $2,379,217 to the Donald Danforth Plant Science Center from March 1, 2022 to February 28, 2025. The grant supports research to develop targeted DNA integration techniques in plants. Specifically, the Center and its sub-awardees—the University of South Carolina Aiken Campus and University of Missouri—will work to engineer hyperactive versions of the Pong transposase proteins and...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award provides $497,039 to Valdosta State University to investigate the biochemical mechanisms by which reactive oxygen species activate the GCN2 protein kinase and its role in regulating protein synthesis in Arabidopsis thaliana as a model plant system. The research aims to enhance understanding of plant stress responses and translational control mechanisms, which could contribute to developing...
- This Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $300,000 in funding to Western University of Health Sciences to conduct collaborative research on the variability and regulation of the plant polyadenylation complex. The research aims to better understand how this complex mediates gene expression and plant responses to environmental and developmental cues, with the goal of improving our knowledge of crop plant growth,...
- This Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) provides $350,000 in funding to New York University (NYU) to develop a "plant-on-a-chip" microfluidic device. The goal is to create a miniaturized "plant factory" that can mimic the hormonal and mechanical environment of plant cells, allowing researchers to study critical functions like cell division and regeneration. The device aims to advance the understanding and...
- The National Science Foundation (NSF) awarded a $259,157 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to Worcester Polytechnic Institute (WPI) for the collaborative research project "TOOLS4CELLS: AN INDUCIBLE DEGRON TOOL FOR PLANT CELL BIOLOGY." The project aims to expand the capabilities of a recently developed tool called E3 DART to control protein degradation in plants, providing the opportunity to manipulate the abundance of protein targets at the...
- This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
The Project Grant award, titled "DEVELOPING AN INTRACELLULAR PROTEIN DELIVERY SYSTEM FOR IN PLANTA PROTEIN-PROTEIN INTERACTION STUDIES", was provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074). The $1,000,000 award, with a project period from September 1, 2025 to August 31, 2028, will support the development of a novel, non-invasive intracellular protein delivery system to enable the study of protein interactions within live plant cells. The system leverages a small, engineered protein called MTD4 to carry functional proteins into plant tissues, allowing researchers to observe protein activity in a physiologically relevant context. This innovation will enhance understanding of plant genomes, foster interdisciplinary education, and support the development of resilient, high-performing crops for a sustainable future. The project involves strong training and outreach components, providing research opportunities for graduate students, postdocs, and undergraduates, as well as public engagement through the Ohio Farm Science Review.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 8/18/25 |