This National Science Foundation (NSF) Biological Sciences program project grant awarded to William Marsh Rice University (Rice University) in the amount of $800,000 will fund the development of a high-throughput approach to build and study synthetic microbial communities. The project aims to create new methods to rapidly construct and understand the interactions within these complex communities of microbes, with the goal of identifying new sources of antibiotics and providing educational and...
This $376,301 project grant awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at the University of Rochester aimed at developing a practical approach for controlling and stabilizing microbial communities. The project leverages plasmid conjugation to dynamically balance microbial growth rates and composition, creating programmable microbial populations that can maintain stability across diverse conditions. Key objectives include computational...
The National Science Foundation awarded a $942,596 CAREER Program grant under its Biological Sciences (CFDA 47.074) federal grant program to William Marsh Rice University in Houston, Texas. The 5-year project will investigate the role of bacterial deaminase toxins in cell physiology and microbial interactions. Specifically, the research aims to characterize the substrate preference and structure of these toxins, explore their biological roles independent of secretion, and develop...
This Project Grant award of $136,600 from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at William Marsh Rice University to develop advanced tools for directly visualizing, quantifying, and correlating DNA dynamics, organization, and gene activity in real-time. The project aims to overcome challenges in studying these essential processes for regulating gene expression and healthy cell function, which have been implicated in various diseases. The...
Rice University was awarded a $1,989,933 project grant from the National Science Foundation Division of Emerging Frontiers under the Biological Sciences federal grant program (CFDA 47.074) for the period of October 1, 2021 through September 30, 2026. The grant will support research to elucidate the rules of cooperation and resiliency in microbial communities through stochastic graph grammars. This work aligns with the Biological Sciences program's goals of advancing the biological sciences and...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded Rice University a $373,174 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to conduct research toward developing lifelike synthetic cells through engineered control of DNA replication from August 15, 2021 to July 31, 2024. The Biological Sciences program aims to advance biological knowledge and understanding of major problems to strengthen the nation's scientific enterprise....
This Project Grant award from the National Science Foundation (CFDA 47.074 Biological Sciences program) provides $325,751 to Williams College to identify, characterize, and engineer plasmid-encoded modulators of natural plasmid transformation in the bacterium Vibrio natriegens. The research will examine how plasmid sequence parameters such as size, genetic cargo, and replication origins impact the efficiency of plasmid natural transformation - the process by which bacteria take up DNA from their...
This $443,477 project grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems will support research and education activities at Rice University from February 1, 2023 through January 31, 2028. The project aims to advance environmental microbiome engineering for wastewater treatment and resource recovery applications. Specifically, the principal investigator will develop and validate novel strategies for harnessing horizontal gene...
This National Science Foundation (NSF) Project Grant award, under the Biological Sciences program (CFDA 47.074), provides $240,000 over three years starting on September 1, 2024 to fund a Postdoctoral Research Fellowship in Biology. The research aims to investigate the effects of bioengineered organisms on community assembly and ecosystem functioning in a soil microbial community. The fellow will use genetic engineering to create microbial consortia and study the impacts on community and...
This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting...