Project Grant 2515959
- This Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), provides $300,000 to the University of Kansas Center for Research Inc. from February 1, 2023 to January 31, 2025. The award will support research investigating delivery and trafficking of DNA introduced to cells from environmental sources using the genetically tractable organism Caenorhabditis elegans. The project aims to gain new...
- This $1.8 million project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research at Cornell University to develop single molecule tools and techniques for studying coronavirus membrane fusion. The goal is to understand the relationship between coronavirus fusion peptide sequence and target host cell membranes at the nanoscale. Specifically, the awardee will identify and measure the physicochemical interactions between the coronavirus spike...
- This $278,344 Project Grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports a research project at Kansas State University (KSU) to investigate the role of heterochromatin in regulating fungal infection and evolution. The project aims to uncover the rules governing genome function in fungi, with the goal of generating new insights into how fungi live, adapt, and cause disease. Key activities include: Providing mentoring and training in...
- The National Science Foundation awarded a $294,100 project grant to the University of Kansas Medical Center Research Institute, Inc. to support research titled "EAGER: ENGINEERING OPTICAL NANOBIOSENSORS FOR DETECTION OF CORONAVIRUS PROTEASES" under the NSF Engineering program (CFDA 47.041). The grant funding will support the development of optical nanobiosensors for detecting coronavirus proteases from March 15, 2021 through October 31, 2022. The NSF Directorate for Engineering seeks...
- The National Science Foundation (NSF) awarded a $1,300,000 project grant to the University of Kansas Center for Research Inc. from March 1, 2024 to February 29, 2028 under the NSF Biological Sciences program (CFDA 47.074). The purpose of this grant is to study how immune defense differs among closely related Drosophila species and to determine the genetic basis for these differences. The research aims to improve understanding of how species evolve to fight infections, which has implications...
- The National Science Foundation awarded a $817,970 project grant to The University of North Carolina at Charlotte under the Biological Sciences federal grant program (CFDA 47.074) for a three-year period from May 1, 2021 to April 30, 2024. The grant will support research studying the evolution of the antiviral pathway in a cnidarian model interacting with diverse viral communities. The Biological Sciences program aims to promote progress in the biological sciences and strengthen the nation's...
- This $900,000 federal Project Grant award was provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) to The Johns Hopkins University. The grant will support research to investigate the mechanistic roles of hyper-divergent regions in gene-by-environment interactions and their impact on adaptation. The project will use cutting-edge genomics, genetic crosses, and high-throughput experiments with nematode species to uncover molecular details on how evolution...
- This $100,000 Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research to develop new theory and predictive models for understanding how environmental pressures shape the evolution of virulence in opportunistic bacterial pathogens. The project aims to: (I) Develop and test predictive models of strain-specific virulence, transmission, and environmental origins for the model pathogen Pseudomonas aeruginosa; and (II)...
- This $400,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research to model the complex dynamics of viruses and bacteria in ancient ocean-like environments. The project aims to identify "keystone" viruses that significantly influence microbial community structure and biogeochemistry in these stable, oxygen-free lake ecosystems. The research will develop innovative mathematical methods to predict...
- This federal Project Grant award, valued at $2,094,250 and administered by the National Institute of General Medical Sciences (NIGMS) under CFDA program 93.859 (Biomedical Research and Research Training), supports research at the University of New Mexico (UNM) into the interactions between the methionine cycle and coronavirus RNA capping mechanisms. The research aims to elucidate the spatiotemporal regulation and quaternary structures of enzyme complexes involved in the methionine cycle, which...
This federal Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program provides $1,000,000.00 to the University of Kansas Center for Research Inc. to determine how the evolution of the coronavirus macrodomain contributes to its biochemical and virological functions. The project will evaluate how viral macrodomains have evolved to develop the ideal biochemical properties that allow them to function during a virus infection, using the mouse coronavirus as a model. The project aims to provide new insights into the fundamental biology of macrodomain enzymes, which could lead to advancements in antiviral drug development. The award has strong educational and community outreach components, including student participation and workshops in phylogenetics. The project will run from August 1, 2025 to July 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.0m | 7/22/25 |