Project Grant 2502989
- The National Science Foundation (NSF) awarded a Project Grant under the Biological Sciences (CFDA 47.074) program to The Johns Hopkins University totaling $856,135. The award will fund research to develop and apply new single-molecule methods to measure protein production in individual live cells, rather than population averages. The goal is to better understand the regulatory mechanisms governing when and where protein production occurs in cells. In addition to the core research, the project...
- The National Science Foundation (NSF) awarded a $630,000 Project Grant under the Biological Sciences (CFDA 47.074) federal grant program to the University of New Mexico (UNM) to develop an advanced optical microscopy system. The project aims to significantly improve the study of protein clustering and interactions on cell membranes, which could advance the understanding of cell signaling and related diseases like cancer. The highly interdisciplinary research will combine the MINFLUX and modal...
- The National Science Foundation awarded the University of Louisville a $358,793 project grant under the Biological Sciences program (CFDA 47.074) to develop a microfluidic platform for dielectric characterization of biological nanoparticles. A team of graduate, undergraduate, and high school students will design and build the system using microfabrication techniques, gaining entrepreneurial training through university programs. The specialized platform will enable fundamental insight into...
- This Project Grant award of $350,000.00 from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports the development of a new method for real-time measurement of endogenous biomolecules in live cells. The "TOOLS4CELLS" project at Tufts University aims to create a novel "turn-on biosensor" technology that can quantify changes in protein levels, such as beta-catenin, with much higher sensitivity and less background noise than existing methods. The...
- This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program provides $410,939 to Clemson University to conduct research on the biophysical mechanisms of membrane protein folding and stability. The project will use advanced single-molecule force spectroscopy techniques, specifically atomic force microscopy, to study how membrane proteins interact with cell membranes and maintain their proper structure. The goal is to gain fundamental biophysical...
- This $1,137,520 National Science Foundation (NSF) project grant awarded to Clemson University under the Biological Sciences program (CFDA 47.074) aims to conduct integrative functional and quantitative genomics research on butterfly wing color and patterning. The work will identify the genetic architecture of a polygenic and polymorphic phenotype found in male butterflies, study the evolutionary processes underlying its adaptive gain, and test hypotheses about how this phenotype is driving...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program is providing $885,642.00 in funding to Trustees of Boston University to conduct a project titled "USING OPTOGENETICS TO CHARACTERIZE SIGNAL PROPAGATION AND CONTROL WITHIN GENE REGULATORY NETWORKS". The project aims to define the underlying principles behind the function of complex biological sensor and regulatory networks, with the goal of using this knowledge to create synthetic organisms for...
- The National Science Foundation awarded a $367,636 Project Grant to the Massachusetts Institute of Technology from March 1, 2021 through February 29, 2024 under the Biological Sciences program (CFDA 47.074). The grant funds collaborative research on multidimensional single-cell phenotyping to elucidate relationships between genomes and phenotypes. The Biological Sciences program aims to advance biological knowledge and understanding of major problems through basic research. This award supports...
- The National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program awarded a $987,578 project grant to The Johns Hopkins University with a project period from July 1, 2025 to June 30, 2028. The research project seeks to obtain quantitative information about the signaling properties of a member of the receptor tyrosine kinase family in response to different ligands. Highly quantitative biophysical methods will be used to understand how diverse extracellular signals...
- The National Science Foundation Division of Integrative Organismal Systems awarded a $206,320 Project Grant to the Donald Danforth Plant Science Center for the period of May 1, 2022 through April 30, 2023. The grant supports collaborative research to develop an artificial chromosome system in Chlamydomonas based on CENH3 tethering under the Biological Sciences program (CFDA 47.074). The Biological Sciences program aims to promote progress in the biological sciences and strengthen the nation's...
The National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) awarded a $926,816 Project Grant to Clemson University to enable a five to ten-fold increase in the number of different biological measurements that can be made simultaneously using widely available fluorescent methods. The project will develop DNA-based "nanoruler" spectral barcodes to enhance multiplexed fluorescence capabilities, with broader impacts related to providing advanced scientific tools and training the next generation of scientists. The project will integrate findings into university courses, provide open-source access to results and tools, and conduct public outreach. This effort supports fundamental and applied biological research by significantly expanding multiplexed experimental capabilities, which could lead to breakthroughs in areas like developmental and tissue biology and microbial community analysis.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $926.8k | 7/28/25 |