Project Grant 2453934
- The National Science Foundation (NSF) awarded a $339,471 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to Ferris State University to support research on the chemoenzymatic fluorination of aromatic compounds. The project, led by Dr. S. Eric Nybo, aims to develop new enzymatic tools for incorporating fluorine atoms into natural products. The research will involve undergraduate students in studying the biosynthesis of organofluorine molecules, training them in NMR...
- This federal Project Grant award, with a total funding amount of $800,000, was provided by the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Berkeley. The purpose of the grant is to support research by Professor John F. Hartwig in the Department of Chemistry, who is developing and studying new transition-metal catalyzed reactions to form carbon-fluorine bonds. This research aims to enable the synthesis of a...
- The National Science Foundation awarded a $512,777 Project Grant to the University of South Dakota under the Mathematical and Physical Sciences program (CFDA 47.049) from July 1, 2023 to June 30, 2026. The grant funds research aimed at developing next-generation fluorinating reagents that are effective, safe and economical for producing organofluorine compounds of medical and materials interest. Specifically, the university will design and prepare an array of fluorinating reagents with tunable...
- The National Science Foundation (NSF) Division of Chemistry awarded a 3-year, $567,231 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the Regents of the University of Minnesota, Office of Sponsored Projects Administration. The grant supports research by William Arnold, William Pomerantz, and Sebastian Behrens to investigate the environmental presence and degradation of mass-produced chemicals, particularly pharmaceuticals and pesticides containing fluorine....
- The National Science Foundation (NSF) is providing a $600,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the Massachusetts Institute of Technology (MIT) for a 4-year research project led by Professor Alexander Radosevich. The project aims to develop inexpensive, earth-abundant chemical catalysts capable of enabling novel bond-making and bond-breaking reactions. Specific research areas include using proton-coupled electron transfer (PCET) to activate C-H...
- This Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $404,662 to Brandeis University to support research exploring novel synthetic approaches for selective functionalization of olefins using stable peroxides. Professor Hao Xu and his students at Brandeis University will develop new iron-catalyzed methods for selective diazidation/diamination and fluoroalkyl transfer reactions on a broad range...
- This $472,369 National Science Foundation Division of Chemistry Project Grant will support research into novel fluorinated functional groups as environmentally benign replacements for persistent and toxic compounds used in pharmaceuticals and agrochemicals. Professor John T. Welch of the University at Albany will investigate the chemical reactivity and polar hydrophobicity of tetrafluoro(trifluoromethyl)sulfanes. Seventh through twelfth grade students from underrepresented and economically...
- The National Science Foundation (NSF) Chemical Synthesis Program has awarded a $550,000 Project Grant to Professor Jon Njardarson of the University of Arizona. The grant supports the development of new asymmetric anionic reaction cascades that leverage readily available feedstock materials and negatively charged reaction partners to produce higher-value fine chemical products. Key objectives include in situ trapping of lithium enamides to expand product types, as well as the formation of...
- The National Science Foundation (NSF) Division of Chemistry is providing a $600,000 Project Grant to Professor Song Lin at Cornell University under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The grant supports the development of new chemical reactions that selectively couple amines to form nitrogen-nitrogen (N-N) bonds, which are prevalent in bioactive natural products, medicines, agrochemicals, and functional materials. The long-term objective is to facilitate...
- Under a $595,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program, Professor Thomas Lectka of Johns Hopkins University will pursue two complementary strategies to selectively modify specific carbon-hydrogen or carbon-carbon bonds within complex molecular structures. The first approach will utilize hydrogen bonding to direct site-selective functionalization reactions, while the second will leverage metal ion binding to deactivate...
The National Science Foundation, through its Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), awarded a $550,000 Project Grant to Professor Mathew J. Vetticatt of Binghamton University to develop a robust suite of novel reactions for incorporating fluorine atoms into organic molecules. The project aims to create an operationally simple radical fluorination reagent, using silver(II) fluoride in acetonitrile, to complement existing nucleophilic and electrophilic fluorination approaches. The proposed research will elucidate the mechanistic details of these newly discovered fluorination reactions, which can convert cheap, widely available chemical feedstocks into high-value fluorine-containing molecules important for drug discovery. The project will provide an excellent platform for training scientists at all levels and advance fundamental understanding of organic reaction mechanisms to enable the discovery of novel chemical transformations.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $550.0k | 7/29/25 |