This $550,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports a research project led by Shuming Chen at Oberlin College. The project aims to develop computational models to better understand and enhance the selectivity of transition metal-catalyzed reactions that can functionalize strong covalent bonds, such as carbon-carbon and carbon-hydrogen bonds. This research has wide-ranging implications for advancing...
Under a $595,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program, Professor Thomas Lectka of Johns Hopkins University will pursue two complementary strategies to selectively modify specific carbon-hydrogen or carbon-carbon bonds within complex molecular structures. The first approach will utilize hydrogen bonding to direct site-selective functionalization reactions, while the second will leverage metal ion binding to deactivate...
The National Science Foundation Division of Chemistry awarded Princeton University $499,999 under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) for the period April 1, 2023 through March 31, 2026. Under this Project Grant, Princeton University will study selective oxidation reactions central to pharmaceutical, fine chemical, and other chemical industry processes. Specifically, the university will design advanced catalysts with high reactivity, selectivity, and...
The National Science Foundation (NSF) awarded a $575,000 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to The Trustees of Columbia University in the City of New York. The grant supports a 3-year research project led by Professor Gerard Parkin to study the synthesis, structure, and reactivity of alkylperoxide, hydroperoxide, and fluoromethyl compounds of earth-abundant metals like magnesium, calcium, and zinc. This research aims to reduce the chemical industry's...
This $575,000 National Science Foundation Division of Chemistry Project Grant supports the development of new methods for the chemical synthesis of cyclic organic molecules at the Massachusetts Institute of Technology from August 1, 2023 to July 31, 2026. Professor Rick L. Danheiser will study new cycloaddition and annulation strategies to provide researchers in academia and industry with more efficient tools for synthesizing medically, agriculturally and industrially important compounds...
This Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) provides $263,809 to Professor Jeffrey Gustafson of San Diego State University to study new approaches for modifying fine chemicals and pharmaceutical intermediates through the catalyst-controlled regioselective functionalization of aromatic compounds. The research aims to develop new chemical reactions and organocatalysts to enable more selective and efficient...
This Project Grant award from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), provides $180,636 to a research team at the University of Illinois at Chicago to develop new reactions that rapidly assemble novel molecules using N-alkenylnitrones and N,O-dialkenylhydroxylamines as reactive intermediates. The team is investigating stereocontrol of new carbon-carbon bond forming reactions, including catalytic...
This Project Grant award, funded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049), supports research at the University of Illinois at Urbana-Champaign led by Professor Scott E. Denmark. The $800,000 award, effective May 1, 2025 through April 30, 2029, aims to develop new catalytic methods for the stereoselective synthesis of pharmaceutically-relevant saturated heterocycles. The research activities focus on three specific aims: (1)...
The National Science Foundation (NSF) Division of Chemistry awarded a $652,777 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of North Carolina at Chapel Hill. Through this 4-year grant, Professor Erik J. Alexanian is developing chemical reagents to enable the selective diversification of polyolefin plastics, such as polyethylene and polypropylene, through C-H bond functionalization. This approach aims to "upcycle" post-consumer...
This $575,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will fund research at the University of California, San Diego to synthesize and study the reactivity of unusual main group elements stabilized by transition metal isocyanide complexes, from July 1, 2023 to June 30, 2026. Specifically, Professor Joshua S. Figueroa will manipulate boron monofluoride and diphosphorus molecules, which are...