Project Grant 2453772

Award Date 7/1/25
Completion Date 6/30/28
Dollars Obligated $600K
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
Buffalo, NY 14260, USA
Similar Awards
The National Science Foundation Division of Chemistry awarded a $400,000 Project Grant to The Research Foundation For The State University Of New York to fund the collaborative research project "UNDERSTANDING THE MOLECULAR RECOGNITION BEHAVIOR OF HOLLOW HELICES" from September 1, 2021 through August 31, 2024. This grant is being administered under the Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the...
The National Science Foundation (NSF) awarded a $543,183 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the Research Foundation for the State University of New York (RF SUNY), which serves as the fiscal agent for SUNY campuses. The grant, awarded on October 1, 2023, supports a study led by Andrew Murkin at the University at Buffalo on the mechanisms and inhibition of organic and enzymatic isomerization reactions. The key products and services to be...
The Research Foundation For The State University Of New York was awarded a $550,000 project grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) to support research on anion-binding macrocycles. Professor Bing Gong of the State University of New York at Buffalo will design macrocyclic molecules to selectively bind anions and transport them across barriers. Undergraduate and graduate students will gain research experience studying how macrocycle...
This three-year, $481,116 National Science Foundation project grant supports research into size-selective catalysis using earth-abundant metals and specially designed macrocyclic ligand families. Funded under the NSF's Mathematical and Physical Sciences program (CFDA 47.049), the work builds on previous studies demonstrating the potential of macrocyclic N-heterocyclic carbene ligands for size-selective catalysis. Professor Steven T. Diver of the University at Buffalo will further develop this...
The National Science Foundation (NSF) Division of Chemistry awarded a $468,099 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to the University of Connecticut. The funding will support the development of new strategies to synthesize synthetic polypeptides, or artificial protein-like polymers, under metal-free, auto-catalyzed conditions. Specifically, the project aims to refine a "helix-guided polymerization" process to enable more efficient and...
The National Science Foundation (NSF) Division of Chemistry awarded a 4-year, $680,000 Project Grant to the University of Wisconsin-Madison to develop new "foldamer" catalysts inspired by the structural diversity of enzymes. Under this grant, Professor Samuel H. Gellman will utilize organic and supramolecular chemistries to prepare bifunctional and trifunctional foldamer catalysts capable of promoting carbon-carbon bond forming reactions. The goal is to enable the development of new...
This $326,557 federal Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences Program (CFDA 47.049) will support research to develop and characterize novel biomaterials made from folded globular proteins. The key objectives are to: (1) experimentally characterize the mechanical response of protein building blocks under varying force, geometry, and solution conditions; (2) directly relate protein domain unfolding to the mechanical properties...
This federal Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program provides $250,000 to Professor Chekan and students at the University of North Carolina Greensboro (UNC-G) to study new enzyme catalysts for crosslinking amino acid side chains in peptides. The researchers will use directed evolution and engineering approaches to improve the substrate scope and catalytic properties of copper-dependent enzymes, with the goal of...
This Project Grant from the National Science Foundation's Mathematical and Physical Sciences Directorate provides $300,000 to fund research on cyclodextrin-poly(ethylene glycol)-based dynamic covalent networks at the University at Buffalo from August 2023 through July 2026. The award aims to advance membrane materials science and sustainability applications through the development and study of polymer networks with dynamic covalent bonds between cyclodextrin and poly(ethylene glycol) building...
The National Science Foundation awarded a 4-year, $575,000 Project Grant to Professor Babak Borhan at Michigan State University (MSU) under the Mathematical and Physical Sciences (CFDA 47.049) program. The project focuses on developing new methodologies to rapidly identify the chirality (three-dimensional shape) of organic molecules, which is critical for understanding their physical and biological characteristics. Key objectives include designing and synthesizing supramolecular sensor...

The National Science Foundation (NSF) awarded a $600,000 Project Grant under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049) to Professor Bing Gong of the State University of New York at Buffalo. The grant supports research to study the function, properties, and catalytic behavior of short polyamides with spirally folded helical conformations, known as "hollow helices." The research aims to develop these synthetic structures as enzyme-like catalysts capable of accelerating chemical transformations by stabilizing transition states, with potential applications in organic synthesis. Key project objectives include enhancing the catalytic efficiency of the hollow helices, exploring their use in the synthesis of chiral mixed acetals, and providing research training opportunities for students. The award period is from July 1, 2025, to June 30, 2028.

Generated 6/24/25, 6:29 AM