This $300,000 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports the development of a new optical microscopy technology called "Space-Time-Pulsed Engineered-Excitation for Diffraction-Free Imaging (SPEEDI)." The technology utilizes exotic space-time wave packets to enable high-resolution fluorescence imaging of deep brain tissue without the light scrambling issues of conventional microscopy. The research aims to advance imaging...
This $407,538 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research and development of a novel optical neuroimaging technology called Diffuse Correlation Spectroscopy (DCS) at Duke University. The goal is to enable deep tissue measurement of blood flow within the brain, which can provide valuable insights into neurological and mental health conditions. The project aims to develop a parallelized DCS system using single-photon...
This National Science Foundation project grant award of $299,323 provides funding for research services at the University of Oklahoma from April 15, 2022 through March 31, 2024. The award is made through the Integrative Activities program (CFDA 47.083), which supports activities to build STEM capacity and broaden participation in research. Specifically, the award will fund the development of a novel mesoscopic imaging technique to investigate functional neuronal connections in the mouse...
The National Science Foundation (NSF) awarded a $634,420 project grant under its Integrative Activities (CFDA 47.083) program to the University of Alabama in Huntsville (UAH) to acquire an advanced confocal microscope system. This high-speed, high-resolution microscope will enable innovative and multidisciplinary research across various scientific disciplines, including neuroscience, microbiology, cell biology, and materials science. The microscope will be integrated into classes and student...
This Project Grant award, funded by the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074), will support the development of an advanced optical microscopy system that combines two cutting-edge imaging techniques: MINFLUX and modal imaging. The $630,000 award, effective from April 15, 2025 to March 31, 2028, will enable researchers at the University of New Mexico to construct this state-of-the-art microscope. The combined MINFLUX and modal imaging system will provide...
This $374,399 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports the development of innovative two-photon microscopy systems with scattering correction capabilities for deep tissue imaging. The University of California, Davis aims to develop high-speed, high-efficiency light modulation hardware and deep learning-based algorithms to optimize light propagation through scattering biological...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $419,038 Project Grant (CFDA 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders) to the University of North Dakota to develop a miniature selective plane illumination fluorescence microscope for high-resolution volumetric imaging in freely behaving mice. The goal is to create a transformative machine learning-augmented miniature adaptive optics light-sheet microscopy platform to...
This $573,147 National Science Foundation Project Grant through the Integrative Activities program (CFDA 47.083) will fund the acquisition of a Zeiss LSM 900 confocal microscope with Airyscan for Queens College of the City University of New York's Core Facility for Imaging, Cell, and Molecular Biology. The microscope will enhance multidisciplinary research and training at the minority-serving institution by enabling new microscopy courses and outreach activities promoting STEM access for...
The University of California, San Diego (UCSD) was awarded a $587,425 Project Grant from the National Science Foundation (NSF) Engineering program (CFDA 47.041) to develop the first dual-modality super-resolution microscopy system, termed Dual-Modality Localized Plasmonic Structured Illumination Microscopy (DM-LPSIM). This new imaging technology will enable simultaneous high-speed super-resolution fluorescence and label-free scattering imaging at the 50-nanometer scale. The DM-LPSIM system...
The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $300,000 EAGER (Early-Concept Grants for Exploratory Research) project grant to The Research Foundation for The State University of New York (RF SUNY) to establish near-ultraviolet (NUV) coherent anti-Stokes Raman scattering (CARS) microscopy for highly sensitive imaging of native biomolecules. This technology will be applied to develop label-free digital pathology for brain...