This $275,000 SBIR Phase I Project Grant, awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a generalized process to formulate and stabilize beneficial microbes for widespread adoption. The project, conducted by Seia Bio Inc., seeks to address the challenge of microbial stability when exposed to stressors such as heat, UV light, shock, and humidity. The proposed R&D will advance the understanding...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $273,910 provides funding to Bluestem Biosciences Inc. to research and develop more energy-efficient methods for the anaerobic bioproduction of valuable organic acids such as 3-hydroxypropionic acid. The goal is to create a biomanufacturing process that can reduce greenhouse gas emissions and reliance on foreign supply chains compared to current petrochemical-based methods for...
This SBIR Phase I award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) provides $275,000 to Caravel Bio, Inc. to develop a novel synthetic biology platform for high-throughput directed evolution of spore-displayed enzymes. The project aims to create customizable enzyme solutions for industrial biocatalyst applications by improving key properties like enzyme activity, stability, and loading density. The technology uses...
This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $274,918 to Cascade Biocatalysts Inc. will fund research and development to demonstrate the commercial feasibility and scalability of a patent-pending approach for stabilizing enzymes through engineered polymer-enzyme interactions. The goal is to enable environmentally sustainable, low-carbon chemical manufacturing processes that utilize enzymes as catalysts, which can decrease...
New Horizon Biotech Inc. received a $256,000 National Science Foundation SBIR Phase I Project Grant to determine performance characteristics during cultivation of living organisms in a novel single-use horizontal modular and pressurizable microbial fermentor. The funding period is from February 15, 2021 through May 31, 2023 under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). This program seeks to advance science, engineering, and technology innovations to address...
The National Science Foundation awarded Opera Bioscience, Inc. $275,000 under the Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a low-cost bacterial production platform for manufacturing high purity recombinant proteins and growth factors. The award period runs from June 15, 2023 through May 31, 2024.
Opera Bioscience will utilize this funding to demonstrate the ability of its innovative protein production platform to solve challenges in traditionally costly and...
The National Science Foundation awarded Ancilia, Inc. a $255,717 Small Business Technology Transfer Phase I Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant will support development of phage-resistant bacterial therapeutics from July 2021 through June 2023. The NSF Technology, Innovation, and Partnerships program seeks to advance science, engineering, and technology innovation to address national challenges. Under this award, Ancilia...
This National Science Foundation (NSF) Small Business Innovation Research (SBIR) Phase I award to Bactria Pharmaceuticals LLC is providing $274,937 to develop therapeutic drugs that restore antibiotic sensitivity in bacteria that cause severe healthcare-associated infections. The goal is to combat antimicrobial resistance in gram-negative pathogens through the use of small molecule efflux pump inhibitors (EPIs). The project involves three key activities: cryo-electron microscopy to understand...
The National Science Foundation (NSF) awarded Pearl Bio, Inc., a biotechnology company, a $274,462 Project Grant under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). The grant funded the development of a next-generation biomanufacturing platform to engineer new microbial organisms and cellular machinery. This platform enables the incorporation of diverse, non-native components into proteins, creating a new class of biological materials for therapeutic development,...
This is a Project Grant award from the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084). The $275,000 award was granted to Terraferma Foods, Inc. on January 15, 2025 to develop a novel platform for accelerating the strain development process for precision fermentation. The project aims to create a high-throughput screening system and apply machine learning to rapidly predict and design signal sequences that enable high-yield...