This $349,996 federal Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program aims to develop a new dental technology to improve oral health through microbial transplantation. The project will test the use of beneficial oral microbes from healthy donor dental plaque to treat conditions like dental decay and gum disease in recipients. The effort will employ a 3D printed system to grow and propagate the transplanted microbes, with the...
The National Science Foundation awarded a $254,360 Project Grant to Quiver Dental, Inc. under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a diagnostic device to measure dental implant stability. The one-year award running from August 1, 2022 to July 31, 2023 aims to complete proof-of-concept demonstration of a reliable and accurate device using vibrational technology to quantify the degree of motion and stability between a dental implant and surrounding...
This Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) provides $249,999 to The Trustees of the University of Pennsylvania for the development of a smart dental implant system. The award will support research and educational activities from September 2022 through August 2025. Specifically, the grantee will build a strategy to prevent peri-implant disease through enhancing soft tissue immunity near dental implants. They will develop an ambulatory care platform...
This Project Grant from the National Science Foundation supports the development of superparamagnetic, antimicrobial nanocomposites and a magnetic toothbrush for synergistic dental care. Awarded $276,000 on June 1, 2022 under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084), the funding will support MNT Smartsolutions LLC through May 31, 2023. The company will develop a biofunctionalized magnetic nanoparticle ferropaste that can efficiently remove oral bacterial biofilms...
This National Science Foundation Project Grant of $255,757 awarded on August 15, 2022 will fund the development of an ultrasound-based point-of-care periodontal imaging device under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084). Stylosonic LLC will develop an integrated device for acoustic imaging of the entire mouth that automatically processes imaging data to assist dentists in assessing gingival health and periodontitis. Key objectives include miniaturizing imaging...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $297,711 Project Grant to Periomics Care LLC under the Oral Diseases and Disorders Research program (CFDA 93.121). The objective of this Phase I study is to develop and evaluate zinc tetraammine difluoride (ZAF) as a non-invasive, aesthetic, and cost-effective alternative to traditional dental caries management strategies. The project aims to determine the mineral loading efficacy of ZAF agents in human dentin to enable...
The federal Project Grant award for $294,632 from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121) is funding the development of an intraoral imaging system to improve the detection and monitoring of dental caries (tooth decay). The award recipient, Greenmark Biomedical Inc., has successfully developed a clinically validated fluorescent mouth rinse that illuminates early active caries lesions. The goal of this...
This Project Grant award of $441,247 from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), supports the development of a clinically-calibrated accelerated fatigue test to predict the clinical performance of dental restorative materials. The key products and services being delivered include: Confirming the repeatability of an accelerated fatigue test for model resin-composite restorations. This will establish...
The National Science Foundation (NSF) awarded a $305,000 Small Business Innovation Research (SBIR) Phase I grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Novaurum Biosciences Incorporated in Somerville, MA. The project aims to develop a novel mammalian cell-based nano-biological coating for implantable medical devices that can inhibit biofilm formation and protect against bacterial infections, including antibiotic-resistant strains, while promoting...
This SBIR Phase I project, funded by the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop an innovative implantable device for treating diabetic foot ulcers (DFUs). The $295,000 grant awarded to Biodynamik, a for-profit small business, will support the design and feasibility testing of a low-profile transverse tibial transport (TTT) implant. This implant leverages the principles of distraction osteogenesis to stimulate soft...