The National Science Foundation awarded a $254,360 Project Grant to Quiver Dental, Inc. under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to develop a diagnostic device to measure dental implant stability. The one-year award running from August 1, 2022 to July 31, 2023 aims to complete proof-of-concept demonstration of a reliable and accurate device using vibrational technology to quantify the degree of motion and stability between a dental implant and surrounding...
This $1,000,000 Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program will support the development of an intraoral device for integrating multimodal data to assess health risks. The project aims to create a micro-robotic system for rapidly and precisely collecting bacterial plaque samples from hard-to-reach areas of the oral cavity. Using artificial intelligence, the collected data will be analyzed to develop a predictive...
This $349,996 federal Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program aims to develop a new dental technology to improve oral health through microbial transplantation. The project will test the use of beneficial oral microbes from healthy donor dental plaque to treat conditions like dental decay and gum disease in recipients. The effort will employ a 3D printed system to grow and propagate the transplanted microbes, with the...
This Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) provides $249,999 to The Trustees of the University of Pennsylvania for the development of a smart dental implant system. The award will support research and educational activities from September 2022 through August 2025. Specifically, the grantee will build a strategy to prevent peri-implant disease through enhancing soft tissue immunity near dental implants. They will develop an ambulatory care platform...
This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) provides $275,000 to T33 Dental, Inc. to validate a novel device and approach for controlling electrically-mediated electrokinetic flow to enhance the delivery of pharmaceuticals and cosmetics into whole human teeth. The project aims to demonstrate the technical feasibility of this approach for enabling deeper and more rapid delivery of clinically relevant molecules into...
This federal Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR), under the Oral Diseases and Disorders Research program (CFDA 93.121), provides $294,632 to Greenmark Biomedical Inc. to develop an intraoral camera system that can detect and monitor early-stage dental caries (tooth decay) using nanoparticle-enhanced imaging and artificial intelligence (AI) software. The key products to be delivered under this award include a minimally viable prototype of...
This Project Grant award from the National Institutes of Health (NIH), under the Trans-NIH Research Support program (CFDA 93.310), provides $297,135 to the Regents of the University of Michigan to conduct research on developing noninvasive quantitative techniques for detecting and monitoring periodontal inflammation. The key goals are to establish ultrasound-derived biomarkers and a machine learning classifier to improve characterization of the inflammatory condition in periodontal tissues....
This $515,926 Project Grant awarded by the National Science Foundation (NSF) Engineering program (CFDA 47.041) will fund research to develop an in vitro gingival (gum) tissue system to study the role of microbial communities on oral health and disease. The 5-year project, beginning June 1, 2024, will be conducted by the University of Massachusetts Lowell's Office of Research Administration-Lowell. The key objectives are: (1) developing and validating a microphysiological system to study oral...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded a $619,347 Project Grant (CFDA 93.121 - Oral Diseases and Disorders Research) to Light Research Inc. (LRI), a for-profit small business in Tucson, Arizona. The grant supports the optimization and commercialization of a compact multimodal intraoral camera that integrates polarized white light imaging, autofluorescence imaging, optical coherence tomography, and near-infrared transillumination imaging modalities. This...
This Project Grant award of $422,665.00 from the National Institute of Dental and Craniofacial Research (NIDCR), under the federal Oral Diseases and Disorders Research program (CFDA 93.121), supports the development of an integrated dental plaque bioanalytical platform for point-of-care diagnostics of oral diseases. The key products and services to be delivered include: Detecting and quantifying hydrogen peroxide and lactate produced by beneficial and pathogenic oral bacteria using innovative...