Project Grant 2418128
Award Date
8/1/24
Completion Date
7/31/28
Dollars Obligated
$1M
Federal Agency
Division of Integrative Organismal Systems
Awardee
Emory University (S352L5PJLMP8)
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Atlanta, GA 30322, USA
Similar Awards
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $229,840 to Brandeis University, commencing on March 15, 2025 and concluding on February 28, 2030, supports research investigating how the heterochromatin protein HP1 helps cells protect epigenetic memory. The project will use the fission yeast model organism to: Engineer synthetic H3K9me binding modules to directly test how genome compartmentalization influences epigenetic memory; Determine how...
This two-year, $1,204,512 National Science Foundation project grant supports research into the robustness and adaptability of the dynamic epigenome through a multiscale approach. Funded under the Biological Sciences program (CFDA 47.074), the award to Brandeis University involves investigating the fundamental rules that guide adaptive epigenetic changes in cells without alterations to the genetic blueprint. The research utilizes high-resolution imaging, microfluidics, and automated culture...
The University of Georgia Research Foundation, Inc. received a $880,000 Project Grant award from the National Science Foundation Division of Molecular and Cellular Biosciences under the Biological Sciences federal grant program (CFDA 47.074). The three-year award running from July 1, 2023 to June 30, 2026 will support research investigating the mechanistic origins and evolution of gene body DNA methylation in plant models. Specifically, the grantee will explore the roles of histone...
This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $500,176 to Eastern Michigan University (EMU) will advance fundamental understanding of the molecular mechanisms regulating gene expression. The 3-year project will study the structure and function of the UHRF1 and UHRF2 epigenetic regulator proteins, which play critical roles in processes like cell cycle control and DNA repair. The research aims to elucidate differences in histone binding...
This $363,057 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports research to unlock the mechanisms of epigenetic memory in human cells. The award will fund a 5-year project at the University of California, Berkeley (UC Berkeley) to investigate how DNA methylation pathways regulate gene expression programs in cancer and embryonic stem cells. Key objectives include dissecting the roles...
The National Science Foundation (NSF) awarded a $300,000 Project Grant under its Biological Sciences program (CFDA 47.074) to the Georgia TECH Research Corporation for the "TOOLS4CELLS: EAGER: A MOLECULAR PURSUIT FOR THE ENGRAM: MICROFLUIDIC TEMPORAL TRANSCRIPTOMICS FOR SINGLE CELL LEARNING" project. This 2-year effort aims to develop innovative microfluidic tools and workflows to investigate the role of non-coding RNA in learning and memory storage in single-celled organisms. Key...
This $200,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at North Carolina State University (NC State) to investigate the genetic and regulatory mechanisms underlying developmental evolution in marine annelid species. The project combines comparative genomics, gene expression, and hybridization assays to uncover the relationship between evolutionary divergence and development, with the goal of understanding how...
This $171,061 five-year (2/15/2025 - 1/31/2030) National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award to the University of Texas at Arlington (UTA) aims to uncover the mechanistic details of how RNA interference (RNAi) and chromatin modifying pathways collaborate to maintain appropriate gene regulation during stress. Using the C. elegans germline as a model, the project will advance understanding of the epigenetic and transcriptional landscape of germ cells...
This $1,203,750 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will fund a research project titled "Identifying Mechanisms Underpinning Epigenetic Homeostasis" at the University of California, Berkeley. The project aims to perform a comprehensive study of the gene regulatory mechanisms that regulate the expression of DNA methylation writer and eraser enzymes to ensure epigenetic...
This $452,399 federal Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Hofstra University to investigate the epigenetic regulation of transposable elements in maize. The research aims to study the RNA-directed DNA methylation (RDDM) induced by naturally occurring maize "killer" alleles and explore the dynamic regulation of transposable element silencing in response to developmental cues. The project will...