This $2,285,694 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at Tufts University to study the relationship between DNA replication and tandem repeat instability. The grantee will combine genetic assays and single-cell live microscopy analysis in a model system to understand how repeat length changes during replication. This dual approach will examine how a repeat's length, propensity to form DNA structures, and orientation...
This $650,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Brooklyn College's Research Foundation of the City University of New York (RFCUNY) to investigate DNA replication in the plant model organism Chlamydomonas reinhardtii. The project, which runs from April 2025 to March 2028, involves a PhD student and several undergraduates studying the precise mechanisms of DNA replication during plant cell division. The...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $367,500 Project Grant to The University of Texas Southwestern Medical Center (UT Southwestern) in Dallas, Texas. The grant, part of the NSF's Biological Sciences funding program (CFDA 47.074), will support research into the conservation of chromatin recruitment mechanisms in metazoan DNA replication licensing factors across evolutionary time, from sea sponge to humans. The project aims to clarify...
The National Science Foundation (NSF) awarded a $1,100,000 Project Grant (CFDA 47.074 - Biological Sciences) to the University of Arkansas for Medical Sciences (UAMS) to study the replication of G-quadruplex DNA by translesion polymerases. This project aims to determine how proteins are recruited to sites of DNA replication and function together to copy G-quadruplex DNA structures, which can act as barriers to accurate genome replication. The research will elucidate the molecular mechanisms...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), is funding research at the Sloan-Kettering Institute for Cancer Research to investigate the molecular mechanisms of eukaryotic chromosome replication. The $1,350,554.00 award will support a 5-year research project that aims to elucidate the intrinsic mechanisms of the eukaryotic DNA replication machinery and its response to various...
This Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training (CFDA 93.859) program, provides $390,000.00 in funding to the University of Colorado-Denver to conduct research on the molecular mechanisms of DNA replication during mitosis. The research aims to uncover how cells complete replication of the entire genome as they enter the cell division phase, which is critical for maintaining genome stability and cell...
This five-year Project Grant from the National Science Foundation, totaling $1,177,451, will support research characterizing rates and patterns of mutation and recombination in Old and New World monkeys. Funded under the Biological Sciences program (CFDA 47.074), the award to Arizona State University from February 2021 through January 2026 will promote progress in the biological sciences by increasing scientific knowledge and understanding of major problems confronting the nation....
This Project Grant from the National Science Foundation Division of Behavioral and Cognitive Sciences provides $142,477 to support collaborative research examining foundations of learning through individual variation, plasticity, and evolution in humans and great apes. Funded under the Social, Behavioral, and Economic Sciences program (CFDA 47.075), this award will support research examining brain organization and its relationship to skill learning in bonobos and chimpanzees. Researchers will...
This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 provides funding for a postdoctoral research fellowship from July 1, 2024 to June 30, 2027. The fellowship will support research and training to investigate the rules governing interactions between genomes, environment, and phenotypes, with a focus on understanding how repetitive DNA sequences, particularly a satellite repeat on the X chromosome of Drosophila melanogaster, influence...
The Research Foundation For The State University Of New York was awarded a $306,181 Project Grant from the National Science Foundation Division of Behavioral and Cognitive Sciences. The grant will fund the project "The Origins and Evolution of Ancient Genomic Structural Variants in Hominins" from August 15, 2021 through July 31, 2024. The project aims to contribute to the scientific strength and welfare of the Nation through advancing basic research in the social, behavioral and...