Project Grant 2414973

Award Date 8/15/24
Completion Date 1/31/26
Dollars Obligated $550K
Federal Grant Program
47.084
Assistance Type
Project Grant
Place of Performance
Clemson, SC 29634, USA
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The National Science Foundation (NSF) awarded a $550,000 Project Grant under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program to Clemson University. The grant, awarded on August 15, 2024, with a completion date of January 31, 2026, funds the development of a novel, automated microwave system for comprehensive single-cell measurement and characterization of high-performing, stable Chinese Hamster Ovary (CHO) cells.

The key products and services to be delivered through this grant include:

  1. Creation of an automated microwave system for rapid, label-free, and non-invasive measurement of CHO cell properties such as size and shape.
  2. Characterization of a variety of CHO cell lines to identify stable, high-producing cell lines based on their unique microwave properties and features.
  3. Development of machine-learning techniques to extract microwave-based markers and features associated with CHO cell performance.

A sub-award of undisclosed amount will support the University of Delaware's contributions to Task 1B, which involves developing the microwave-based CHO cell measurement and selection capabilities. This project aims to significantly reduce pharmaceutical companies' time and costs in enhancing drug quality, yield, and development, especially for rare disease treatments, ultimately leading to more affordable and accessible healthcare.

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