This $768,681 Project Grant was awarded by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) program. The grant was awarded to the University of Colorado-Denver to develop an integrated, automated analysis platform for biomolecular nuclear magnetic resonance (NMR) studies. The key objectives are to: Develop an automated and integrated analytical platform for biomolecular NMR that utilizes AI/ML/CV-based techniques for chemical shift assignments, AI/ML/CV-assisted homomer structure determination, and provides a user-friendly interface for NMR-based structure and dynamics studies. Develop and employ advanced computer science techniques in biomolecular NMR, including a new multidimensional NMR data format, CV-based spectral quality enhancement, and implementation of new workflows using CV/ML techniques. Effectively distribute the software deliverables through web servers and plugin repositories to push biomedical sciences forward and enable broader adoption of the intuitive POKY software suite. The award period runs from September 15, 2024 to August 31, 2027. This project aims to advance the accessibility and automation of powerful NMR methods for studying biomolecular structure, function, and dynamics, which is crucial for addressing challenges in areas like environmental preservation, food production, and disease treatment.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $768.7k | 8/2/24 |