The University of Massachusetts Dartmouth was awarded a $557,571 Project Grant from the National Science Foundation to support the "COLLABORATIVE RESEARCH: CIBR: INCORPORATING CRYSTALLOGRAPHY AND CRYO-EM TOOLS INTO FOLDIT" project. The grant was awarded on June 1, 2021 with a completion date of May 31, 2024 under the Biological Sciences program (CFDA 47.074). The project aims to promote progress in the biological sciences by increasing scientific knowledge and enhancing understanding...
The National Science Foundation awarded a $335,720 project grant to the University of Denver under the Biological Sciences federal grant program (CFDA 47.074) for work beginning August 1, 2021 through July 31, 2024. The grant will support research applying quantitative imaging methods to identify molecular components of multi-vesicular body fusion sites. The Biological Sciences program aims to advance biological knowledge and understanding of major problems through basic research, consistent...
Duke University was awarded a three-year, $750,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences under the Biological Sciences federal grant program (CFDA 47.074). The grant aims to support research transitioning from single-molecule force spectroscopy to single-particle cryogenic electron microscopy. The Biological Sciences program seeks to promote advancement in the biological sciences and strengthen the national scientific enterprise through...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $785,201 Project Grant to The Regents of the University of Colorado to support research titled "Collaborative Research: Understanding Protein Mechanical Stability and Its Impact on Secretion." The two-year grant running from January 15, 2022 to December 31, 2024 will fund research under the Biological Sciences program (CFDA 47.074). The Biological Sciences program aims to promote progress in the...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $206,912 Project Grant under the Biological Sciences (CFDA 47.074) program to the University of North Carolina at Chapel Hill. The three-year grant, effective August 1, 2023 through July 31, 2026, supports collaborative research to enhance the understanding of protein structures and behaviors at extreme temperature and pressure conditions. The research aims to develop rules for predicting protein...
The National Science Foundation awarded a $1.3 million Project Grant to the University of Colorado Denver under the Biological Sciences federal grant program (CFDA 47.074) for the period of July 15, 2021 through June 30, 2026. The grant funds research into protein degradation during the maternal-to-zygotic transition, as part of the NSF's mission to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing knowledge and understanding of...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $710,128 Project Grant under the Biological Sciences (CFDA 47.074) program to The Research Foundation For The State University Of New York (SUNY) to conduct collaborative research on the "Energy Landscapes of Designed Cold Unfolding Proteins." The research aims to enhance understanding of the distinct three-dimensional shapes that proteins can adopt at extreme cold temperatures and high...
This $100,000 Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program supports the development of deep learning-based "consistency models" to simulate the long-time-scale dynamics of protein structures. The project aims to overcome the limitations of traditional molecular dynamics (MD) simulations, which are constrained by small time steps and unable to capture crucial long-duration protein behaviors like folding and...
The National Science Foundation awarded Northwestern University a $525,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to develop protein crystallization programmed with DNA. This three-year award beginning June 1, 2021 will support research to promote progress in the mathematical and physical sciences by increasing understanding of major problems through the development of new techniques to crystallize proteins using DNA programming. The University will...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $221,474 Project Grant to the University of Vermont & State Agricultural College (UVM) for the period of August 1, 2023 to July 31, 2026 under the Biological Sciences program (CFDA 47.074). The primary objective of this grant is to enable the principal investigator to acquire expertise in utilizing single-particle cryo-electron microscopy (cryo-EM) techniques to elucidate the molecular structures...