Project Grant 2407938
- The National Science Foundation (NSF) Engineering program (CFDA 47.041) awarded a $134,514 Project Grant to the Board of Regents of the University of Nebraska, operating as the University of Nebraska, to conduct research on "Collaborative Research: Ultrasound Driven Microbubble Clusters for Biomedical Applications" beginning May 1, 2024. The project aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation...
- This National Science Foundation (NSF) Project Grant award of $275,000 to North Carolina State University (NC State) aims to study the feasibility of using sound waves to remotely control and propel microrobots through blood vessels. The goal is to develop microrobots capable of delivering drugs and providing wireless electrical stimulation to the nervous system, without requiring invasive surgery. The research plan includes three key objectives: Investigating acoustic mechanisms to enable...
- The National Science Foundation (NSF) Directorate for Engineering (CFDA 47.041) awarded a $275,000 project grant to the University of Pittsburgh to study the feasibility of using sound waves to move microrobots in blood vessels for intravascular neuromodulation. The 3-year project aims to investigate acoustic mechanisms for microrobot propulsion, remote drug delivery, and energy harvesting. The research will create data-driven models and controllers to enable microrobots to reach targeted...
- This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) provides $199,930 to the University of Chicago to assess microbubble-induced stresses on soft materials like tissue, in order to support the development of regulatory guidelines for bubble-based medical devices like therapeutic ultrasound systems. The key objectives are to: 1) develop and characterize a mechanophore-based tissue phantom to quantify microbubble-induced deformation, 2)...
- This $516,762 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports fundamental research at the University of Central Florida (UCF) to develop a new ultrasonic shearing method for scalable manufacturing of uniform-sized nanobubbles. The research aims to advance nanobubble production capabilities, particularly for biomedical applications like drug delivery and medical imaging. Key aspects include computational modeling of the ultrasonic...
- The National Science Foundation (NSF) awarded a $500,000 Project Grant to the University of California, San Diego (UCSD) under the Engineering (CFDA #47.041) program to design, fabricate, and evaluate acoustic-to-optical nanoscale transducers. The goal of this 3-year project is to develop novel micro-auscultation devices that can efficiently convert weak sound waves into optical signals, enabling the detection and interpretation of acoustic signatures from small biological objects like cells,...
- The National Science Foundation (NSF) awarded a $199,940 Project Grant to Bucknell University under the Engineering (CFDA 47.041) program. The grant supports research to investigate the effects of low-frequency, low-intensity ultrasound on the interaction between endothelial cells and macrophages, which is important for understanding the biological mechanisms behind the use of ultrasound therapy to promote wound healing. The research aims to characterize how ultrasound affects the pro-angiogenic...
- The National Science Foundation (NSF) awarded a $335,976 Project Grant under the Engineering CFDA Program (47.041) to the Regents of the University of California, Riverside (UC Riverside) for a 3-year period from October 1, 2023 to September 30, 2026. This grant will fund research to investigate the dynamics of particulate suspensions confined by flexible elastic membranes, which are common in biological micro-scale environments. The project aims to develop a fundamental understanding of the...
- This National Science Foundation Project Grant of $185,120 awarded on February 1, 2023 will fund research to understand the fundamental physics of acousto-magnetic microswimmers and realize precise, tunable motion at microscales. Under the NSF's Integrative Activities program (CFDA 47.083), which seeks to enhance STEM competitiveness through critical infrastructure development, the grant will support an assistant professor fellowship and graduate student training at the University of...
- This $220,000 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) aims to advance the understanding of how soft, deformable particles, such as oil droplets and cells, move through complex environments consisting of narrow constrictions and obstacles. The award to Emory University will systematically investigate the flow of bubbles and droplets through obstacle arrays, studying the effects of particle surface tension, obstacle density, size, and...
The National Science Foundation (NSF) has awarded a $266,856 Project Grant to the San Diego State University Research Foundation under the NSF Engineering program (CFDA 47.041) for the period of May 1, 2024 to April 30, 2027. The grant aims to investigate the relationship between acoustically generated force fields, deformable vessel wall mechanics, and bubble oscillation dynamics to understand how microbubble clusters can be used to navigate through blood vessels. The research team will leverage advanced computer simulations to assess the feasibility of microbubble navigation in blood vessels under physiological conditions and biocompatible acoustic power levels. This project is expected to provide a comprehensive understanding of the physical mechanisms and parameters that govern microbubble cluster motion in blood vessels and relate this motion to external acoustic fields. Additionally, the project will create research and training opportunities for undergraduate and graduate students, particularly those from underrepresented groups, and engage the general public through outreach activities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $266.9k | 5/8/24 |