This $399,935 National Science Foundation (NSF) Project Grant Award under the Computer and Information Science and Engineering program (CFDA 47.070) aims to develop a portable and cost-effective biomedical diagnostic system in the form of an integrated lab-on-a-chip platform produced using additive manufacturing techniques. The key products and services to be delivered include: Advancing 3D manufacturing techniques, particularly in electrode printing, to enhance fabrication precision and...
The National Science Foundation (NSF) awarded a three-year, $449,999 Project Grant under their Engineering program (CFDA 47.041) to the University of Cincinnati to develop an implantable biosensor platform that can continuously monitor various biomarkers in the body for over a year. The project aims to create a new class of long-lasting aptamer-based sensors protected by robust porous oxide coatings, which would enable the first practical implantable monitoring system for managing chronic...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $448,818 to The Regents of the University of California, Berkeley (UC Berkeley) to develop a miniaturized, sensitive, and user-friendly electromagnetic (EM) sensing platform for rapid bacterial diagnostics. The project aims to combine physics-based dielectric spectroscopy and biochemistry-based magnetic nanoparticle detection to distinguish unique bacterial phenotypes and surface...
This National Science Foundation (NSF) CAREER Award (CFDA 47.041 - Engineering) provides $242,687 to the University of Massachusetts to develop a novel nanopore biosensor technology for the ultrasensitive, multiplex detection of infectious disease biomarkers at the point-of-care. The key goals are to: (1) optimize a nanopore sensor with high sensitivity, robustness, and reproducibility; (2) enable sensitive and specific biomarker detection through automated immunoprecipitation and novel signal...
The University of California Irvine received a $360,000 Project Grant award from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems on January 15, 2022 to fund the development of The Aptamer Bioresistor. The project aims to create a broadly applicable protein biosensor with simplified dip-and-read functionality for point-of-care diagnostics. The funding supports research under the NSF's Engineering program (CFDA 47.041) and will allow the...
This $500,000 Project Grant award from the National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) program supports the development of a novel materials-based sensing system for detecting a variety of analytes or physiological states in biological fluids. The multidisciplinary team from Lehigh University, led by researchers in chemistry, materials science, bioengineering, and computer science, aims to create an initially "analyte-agnostic" nanosensor...
The National Science Foundation (NSF), under its Engineering program (CFDA 47.041), awarded a $429,832 Project Grant to the University of Massachusetts (UMass) to develop a novel method for rapid and sensitive detection of nucleic acids such as DNA and RNA. The main objectives of the 5-year project are to: Determine the nanomechanoelectrical transduction principle of nucleic-acid nanostructures tethered to a graphene transistor and oscillating in an electric field. Achieve rapid,...
This National Science Foundation (NSF) Project Grant award for $380,074, awarded on September 1, 2024, aims to develop a platform for instrument-free, easy-to-interpret quantitative analysis of molecular biomarkers. The project will produce a general methodology adaptable to a range of molecular targets, including potential new agents. The key products to be delivered include: A "yes/no" output for quantitative measurement, enabled through stoichiometry and negative cooperativity-based...
The federal Project Grant award R01EB037031, provided by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286), will develop living biosensors capable of detecting and analyzing DNA from raw samples without requiring sample purification or specialized equipment. The $257,807 award, spanning from April 2025 to March 2029, will focus on demonstrating the...
This $1,500,000 Project Grant awarded by the National Science Foundation's (NSF) Division of Materials Research under the Mathematical and Physical Sciences Program (CFDA 47.049) aims to accelerate the discovery and optimization of biosensor materials through a closed-loop computational and experimental approach. The key objectives are to: 1) understand the effect of two-dimensional transition metal dichalcogenide (TMD) functionalization and doping on nanoscale interactions with biomolecules, 2)...