Project Grant 2402543

Award Date 8/1/24
Completion Date 7/31/28
Dollars Obligated $947K
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Los Angeles, CA 90095, USA
Similar Awards
This $1,269,993 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research to understand the molecular basis of how plant cells establish the division plane during cell division. The project aims to dissect the function of cytoskeletal motor assemblies at the cortical division site and determine how they connect to molecules in the phragmoplast, the structure that forms the new cell wall during cytokinesis. Researchers at...
This Project Grant award from the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) provides $384,431 to Wellesley College to conduct research on the role of interphase node proteins in the localization of the NDR-family kinase Sid2p during cytokinesis. The project aims to characterize Sid2p recruitment to the division site, evaluate the effect on contractile ring constriction, and identify binding domains between scaffold proteins and Sid2p. The research will...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $1,004,927 Project Grant to The Johns Hopkins University from July 1, 2021 to June 30, 2025. The grant supports research titled "Probing Phosphorylation Events in Biological Membranes" under the Biological Sciences program (CFDA 47.074). The goal of the Biological Sciences program is to promote progress in the biological sciences and strengthen the nation's scientific enterprise by increasing...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $438,629.00 to the University of Massachusetts to investigate the fundamental mechano-molecular mechanisms of cell division. The project aims to characterize the functional contributions of large intrinsically disordered protein regions at the kinetochore and perichromosomal layer, as well as study the regulation...
This $419,168 Project Grant, awarded by the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences under CFDA Program 47.074 Biological Sciences, supports a collaborative research project to study the multiscale mechanics of septin assembly and curvature sensing in biological cells. The project aims to develop a multiscale mechanical model of septin assembly and curvature sensing across three scales: the molecular scale, the filament scale, and the system scale. The...
This $448,150 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop a DNA-based toolbox for the rapid and precise modulation of cell membrane protein-protein interactions (PPIs). The goal is to establish a modular approach using antibodies and aptamers to enable targeted DNA barcoding of cell membrane proteins, particularly receptor tyrosine kinases. This will allow for the controlled stabilization of specific PPI pairs on living...
The National Science Foundation awarded a $565,000 Project Grant to Princeton University from May 2021 through April 2024 under the Biological Sciences federal grant program (CFDA 47.074). This funding supports comparative analysis of endocytic trafficking during cell division through collaborative research. The goal of the Biological Sciences program is to promote progress in the biological sciences and strengthen the nation's scientific enterprise by increasing knowledge and understanding of...
This $1,259,550 Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training program (CFDA 93.859) will fund a 5-year research project at the University of Washington to study the role of protein phosphorylation in regulating the cellular proteome. The research aims to: 1) identify phosphorylation sites relevant to protein function at a proteomic scale, 2) examine how phosphorylation regulates multi-level proteome organization,...
This National Science Foundation Project Grant of $276,000 supports a postdoctoral fellowship in biology for fiscal years 2022 through 2024 under the Biological Sciences program (CFDA 47.074). The fellowship will fund research and training investigating the spatiotemporal coordination of cell and chloroplast division in the green alga Chlamydomonas reinhardtii. Using gene editing, live cell microscopy, and other techniques, the fellow will test hypotheses about cytoskeletal structures...
This National Science Foundation (NSF) Project Grant award under the Engineering program (CFDA 47.041) supports basic research to uncover the mechanisms by which mechanical forces at the protein level regulate cell mechanics and direct tissue-scale behaviors. The $616,151 award, with a project period from September 1, 2024 to August 31, 2027, will fund an interdisciplinary study leveraging molecular biology, bioengineering, materials science, and computational approaches. The research will...

This federal Project Grant award of $946,895 from the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences (CFDA 47.074 Biological Sciences) will fund research to advance the understanding of protein phosphorylation and its role in coordinating cell division. The project aims to identify new enzymes that carry out phosphorylation and the substrate proteins they modify to ensure proper cell division. Researchers will employ computational, biochemical, proteomic, and cell biological approaches to elucidate the "phospho-circuitry" that governs cell division. This project will produce large phosphoproteomic datasets and novel computational pipelines that will be made freely available to the scientific community, contributing to broader advancements in molecular and cellular biology. The award, with a performance period from August 1, 2024 to July 31, 2028, will also provide educational, mentoring, and career development opportunities for diverse high school, undergraduate, and graduate students.

Generated 5/13/25, 2:27 AM