This $380,000 Project Grant awarded by the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences program (CFDA 47.049) supports Louisiana State University's research on new organic synthetic reactions using epoxides. The grant enables Professor Rendy Kartika and his team to investigate the development of stereoselective transformations of epoxides into value-added organochlorine heterocyclic compounds, such as tetrahydropyrans, with potential...
The National Science Foundation (NSF) awarded a $513,894 Project Grant under its Mathematical and Physical Sciences program (CFDA 47.049) to Tufts University. This 3-year grant, effective July 1, 2023, supports Professor Clay S. Bennett's research to develop new methods for synthesizing deoxy sugars - an important component of many biologically active natural products. The project aims to expand upon approaches that activate sugar hemiacetals as glycosyl sulfonates or tert-butyldimethylsilyl...
This $575,000 project grant awarded by the National Science Foundation's (NSF) Division of Chemistry (CFDA 47.049 - Mathematical and Physical Sciences) will support a research effort led by Professor George O'Doherty at Northeastern University to develop novel synthetic methods for the asymmetric synthesis of oligosaccharide structures. The project aims to enable the efficient, de novo construction of both natural and unnatural oligosaccharide motifs, which have important applications in biology...
The National Science Foundation awarded a $575,000 Project Grant to the University of Colorado Boulder under the Mathematical and Physical Sciences program (CFDA 47.049) from July 1, 2023 to June 30, 2026. The grant funds fundamental research on the development of new stereoselective synthesis methods for challenging carbohydrate and glycomimetic systems of biomedical significance. Principal Investigator Maciej Walczak and his team will focus on cross-coupling reactions using stereodefined...
The National Science Foundation awarded Louisiana State University a $559,109 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049). The grant will fund research from June 2021 through May 2024 to develop new methods for 1,2-cis-selective glycosylation using protecting groups, Lewis bases, and backside attack strategies. The Mathematical and Physical Sciences program aims to strengthen the nation's scientific enterprise by increasing fundamental knowledge in...
The National Science Foundation (NSF) awarded a $536,604 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to Saint Louis University. The grant, awarded on July 1, 2024, will support research by Professor Alexei Demchenko to develop new methods for stereocontrolled glycosylation. The project aims to investigate mechanistic and practical aspects of two novel glycosylation reactions, the cooperatively catalyzed Koenigs-Knorr (4K) reaction and the H-bond-mediated...
This Project Grant award, funded by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences grant program (CFDA 47.049), supports Professor Abigail G. Doyle at the University of California, Los Angeles (UCLA) in developing novel synthetic reactions that use visible light and photocatalysts to access high-energy, polar reactive intermediates. The $630,000 award will fund the development of several key transformations, including a desaturation...
This National Science Foundation (NSF) Project Grant, awarded under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), provides $587,497 to Louisiana State University (LSU) and Appalachian State University to develop new fluorescent dyes called BORon DIpyrrole methenes (BoDIPYs) for use in biology and materials science. The key aims are to: 1) Design and synthesize new fluorinated BODIPY dyes and derivatives, 2) Investigate their photophysical and chemical properties,...
The National Science Foundation (NSF) awarded a $575,000 project grant under its Mathematical and Physical Sciences (MPS) program to the University of Wisconsin-Madison to study the use of light in organic synthesis. Under this 3-year award effective July 1, 2024, Professor Tehshik Yoon and his team will design novel photocatalysts that can interact directly with small molecules to control how they react and form more complex products. The research aims to transform discovery in pharmaceutical...
This Project Grant from the National Science Foundation Division of Chemistry, titled "SYNTHESIS, PROPERTIES AND DYNAMICS OF BODIPY-BASED FLUOROPHORES," provides $470,000 in funding from September 1, 2021 to August 31, 2024. The award supports work under the Mathematical and Physical Sciences program (CFDA 47.049) to advance the progress of these sciences and strengthen the Nation's scientific enterprise through increased knowledge and understanding of major problems. Specifically, the...