Project Grant 2348319

Award Date 7/1/24
Completion Date 6/30/27
Dollars Obligated $450K
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Columbia, MO 65211, USA
Similar Awards
This $300,000 Project Grant awarded by the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) supports research to develop novel methods for genetically modifying plants using the parasitic plant Cuscuta campestris, also known as dodder. The key goals are to 1) stably transform the dodder plant to enable host gene editing, 2) create a dodder protoplast system for rapid screening of gene editing constructs, and 3) develop a dodder-mediated gene editing system....
This federal Project Grant award from the National Science Foundation (CFDA 47.074 - Biological Sciences) provides $250,000 to Virginia Polytechnic Institute & State University (Virginia Tech) to develop novel methods of plant genome editing enabled by the parasitic plant Cuscuta campestris (dodder). The key objectives of this 3-year project are to: 1) achieve stable transformation of dodder to enable host gene editing, 2) develop a dodder protoplast system for rapid screening of gene...
This Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research on the genomics of host-specific response and adaptation in the parasitic agricultural pest, Cuscuta (commonly known as dodder). The $599,720 award to the University of Massachusetts will fund a collaborative research project with three main objectives: 1) profiling the diversity of trans-species microRNAs across Cuscuta populations and identifying their host mRNA...
This federal Project Grant award of $1,192,499.00 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) supports research by the Donald Danforth Plant Science Center in Missouri to develop epigenetic editing tools for crop improvement. The key objectives of this 4-year project are to: 1) Expand epigenetic editing technologies to other crop species beyond cassava, such as rice and tomato, to enable disease resistance; 2) Demonstrate additional applications of...
The National Science Foundation awarded a $307,400 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Missouri System to develop epigenetic editing tools for improving crop plants. The project aims to expand the capabilities of genome editing by enabling targeted changes in gene expression, rather than just DNA sequence, to generate novel traits in important crops like rice and tomato. Key objectives include adapting the epigenetic editing approach...
This federal Project Grant award, valued at $1,684,000 and provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports collaborative research by The Pennsylvania State University on host-specific response and adaptation in the parasitic agricultural pest, Cuscuta (commonly known as dodder). The key research aims are to: 1) profile the diversity of trans-species microRNAs across Cuscuta populations and identify their host mRNA targets, 2) resequence...
This $132,500 Project Grant was awarded by the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) to Rutgers, The State University. The grant supports a 3-year collaborative research project to study the genetic mechanisms underlying host-specific response and adaptation in the parasitic agricultural pest, Cuscuta (commonly known as dodder). The research team will profile the diversity of trans-species microRNAs across Cuscuta populations, resequence Cuscuta...
This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $2,379,217 to the Donald Danforth Plant Science Center from March 1, 2022 to February 28, 2025. The grant supports research to develop targeted DNA integration techniques in plants. Specifically, the Center and its sub-awardees—the University of South Carolina Aiken Campus and University of Missouri—will work to engineer hyperactive versions of the Pong transposase proteins and...
This Project Grant award in the amount of $1,211,545.00 from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop highly efficient and robust Prime Editing (PE) systems in rice, tomato, and poplar plants. PE is a cutting-edge CRISPR/Cas gene editing technology that enables precise replacement, addition, or removal of specific DNA sequences. The project objectives are to optimize PE proteins, improve PE guide RNA structure and expression, and modify...
This three-year, $1.8 million project grant from the National Science Foundation Division of Integrative Organismal Systems aims to develop rapid transformation and gene editing techniques in maize through the Biological Sciences program (CFDA 47.074). The University of Missouri System will work to establish a system for precisely inserting transgenes and editing genes at predetermined sites in the genome of maize. Researchers will create "landing pads" on five chromosomes of a...

This Project Grant, awarded by the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074), aims to develop novel methods for plant genome editing using the parasitic plant Cuscuta campestris (dodder). The $450,000 award, effective July 1, 2024 through June 30, 2027, will enable researchers at the University of Missouri System to:

  1. Achieve stable transformation of dodder to enable its use in host gene editing;
  2. Develop a dodder protoplast system for rapid screening of gene editing constructs; and
  3. Establish a dodder-mediated plant gene editing system.

The project seeks to leverage dodder's ability to transfer various molecules, including proteins and RNAs, to a wide range of host plant species. If successful, this research could establish a novel, broadly applicable approach for genetically modifying plants that is simpler and faster than current techniques. The project also includes an outreach component to engage refugee students in plant science activities at the University of Missouri.

Generated 4/8/25, 4:49 AM