Project Grant 2340149
- This $487,795 award from the National Science Foundation (NSF) Engineering grant program (CFDA 47.041) supports Arizona State University in developing innovative ex vivo models of the tumor microenvironment (TME). The project aims to mechanistically understand how biophysical cues and signaling between stromal and immune cells contribute to the transition of tumor cells into an invasive phenotype, as well as explore how stromal cell function induces pathway signatures in tumor cells leading to...
- This National Science Foundation Project Grant of $606,649 will support the development of an engineered cyber-physical system combining advanced biological models and artificial intelligence methods to enable precision medicine for cancer treatment. Awarded under the Computer and Information Science and Engineering program, the funding will be used by Brigham and Women's Hospital and its parent organization Partners Healthcare System from October 2022 to September 2025. Specifically, the...
- This $600,000 Project Grant award from the National Science Foundation's Division of Information and Intelligent Systems (CFDA #47.070 - Computer and Information Science and Engineering) supports the Massachusetts Institute of Technology (MIT) in developing a cyber physical system to remotely control cellular processes and create synthetic pancreatic tissue. The research aims to overcome challenges in recreating complex 3D tissue structures by using swarms of microrobots to regulate the...
- This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award of $575,000 to the New Jersey Institute of Technology (NJIT) will study how the microstructure and interstitial fluid pressure gradient impact cell invasion in a bioprinted tumor-on-a-chip model. The key products and services to be delivered include: Developing a 3D bioprinted tumor spheroid microtissue model with controlled microstructure and tunable fluid-induced pressure. This will involve...
- This $274,594 Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) program supports research and development of an innovative technology for cancer diagnosis and treatment. The project aims to improve molecular profiling and clinical laboratory testing of cancer samples by optimizing microdissection techniques. The research will focus on modeling and optimizing the opto-thermal-mechanical interactions involved in microdissection to...
- This Project Grant award of $275,956.00 from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program supports the development of an engineered cyber-physical system that combines advanced biological models with state-of-the-art artificial intelligence methods for predictive, automated screening of anti-cancer drugs and optimizing their dosing. The goal is to realize a precision medicine paradigm that can improve health outcomes and reduce treatment...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award of $275,000 to Cerflux Inc. aims to develop a personalized cancer treatment screening platform. The project will establish guidelines for handling solid tumor biopsy samples, generate 3D bioprinted tumor models for validation, and demonstrate the platform's ability to match patients with the most effective cancer treatments before treatment begins. This innovative approach has the...
- Federal Grant Award Summary The National Science Foundation's Directorate for Chemical, Bioengineering, Environmental, and Transport Systems (CBETS) awarded $538,930 to the University of Alabama in Huntsville under CFDA 47.041 (Engineering) on August 1, 2026, for a Faculty Early Career Development (CAREER) project investigating circulating tumor cell (CTC) clusters during metastatic migration. The research will deliver computational modeling and artificial intelligence frameworks to simulate CTC...
- This $175,000 National Science Foundation project grant supports the development of multi-modal soft tissue characterization technologies for non-invasive breast imaging at the University of Massachusetts Dartmouth from April 2022 through March 2024. Funded under the NSF's Computer and Information Science and Engineering program (CFDA 47.070), the research aims to establish optimization algorithms and parameters for visualizing breast tissue cross-sections non-invasively using an integrated...
- This National Science Foundation Engineering Education and Centers award provides $463,231 to the New Jersey Institute of Technology through April 2025 to support an Undergraduate Research Experiences for Undergraduates Site project focused on cancer diagnosis and therapeutic intervention research. As part of the NSF's Engineering grant program (CFDA 47.041), 10 undergraduate students annually will engage in 10-week research experiences in fields like physics, biochemistry, and various...
The National Science Foundation (NSF) awarded a 5-year, $360,942 CAREER grant to the University of Wisconsin-Milwaukee (UWM) under the Computer and Information Science and Engineering (CISE) program (CFDA 47.070). This grant supports the development of a virtual model of human tumor tissue to enhance understanding of tumor malignancy and advance early diagnosis and treatment of pancreatic ductal adenocarcinoma. The project aims to create a personalized, in-silico model of tumor physiology that can replicate the complexity and heterogeneity of human tumors. This virtual tissue platform will enable mechanistic studies, simulated disease progression screening, and safe evaluation of new treatments, while also providing early STEM research experiences for undergraduate students. The project leverages advanced computational techniques to overcome limitations of traditional in-vitro and animal models. No sub-awards are planned under this grant.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $360.9k | 1/17/24 |