Project Grant 2339836
Award Date
5/1/24
Completion Date
4/30/29
Dollars Obligated
$720K
Federal Agency
Division of Civil, Mechanical, and Manufacturing Innovation
Federal Grant Program
47.041
Assistance Type
Project Grant
Place of Performance
Philadelphia, PA 19104, USA
Similar Awards
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) is providing $612,979 to Cornell University to investigate the role of acetylcholine signaling in osteocyte mechanotransduction and bone remodeling. The research aims to characterize the relationship between cholinergic nerves and osteocytes in bone tissue, examine the effects of acetylcholine signaling on osteocyte calcium responses to mechanical loading, and study the impact of...
The National Science Foundation awarded a $280,774 Project Grant to the University of Colorado Denver under the Engineering program (CFDA 47.041) for research determining the impacts of lacunar-canalicular remodeling on bone fracture toughness. The three-year award beginning September 15, 2021 will fund collaborative research between the University of Colorado Denver's Department of Mechanical Engineering and the Regents of the University of Colorado to analyze how changes to the...
This $150,001 EAGER Project Grant award, provided by the National Science Foundation (NSF) through its Mathematical and Physical Sciences (CFDA 47.049) program, supports research to observe the movement and collective behavior of multinucleated osteoclast cells in controlled laboratory settings. The project, led by researchers at Georgia Tech Research Corporation, aims to advance the fundamental understanding of bone resorption processes by examining how individual and collective osteoclast...
This $160,000 Project Grant award from the National Science Foundation (NSF) Integrative Activities (CFDA 47.083) program supports collaborative research at Boise State University to develop data-driven "mechanomics" approaches for uncovering age-related mechanical regulation of bone and stem cell behavior. The research aims to quantify intracellular mechanical forces and their impact on cellular protein production and the extracellular environment, with the goal of enabling...
This Project Grant award from the National Science Foundation (NSF) Division of Materials Research, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $322,382 to the University of Connecticut Health Center (UCHC) from September 1, 2023 through August 31, 2026.
The goals of this collaborative research project are to use computer modeling and high-energy synchrotron X-ray diffraction experiments to better understand how the incorporation of cobalt (Co) and chromium...
This National Science Foundation Project Grant of $615,796 will fund research at The Pennsylvania State University from August 2022 to July 2027 under the Engineering (47.041) federal grant program. The research aims to investigate the role of architecture in the fracture behavior of bio-inspired nested cylindrical structures made from brittle materials. Specifically, the grantee will examine the toughening effects of various geometries, roughness, and material properties in marine spicule...
This National Science Foundation (NSF) Faculty Early Career Development (CAREER) Program grant, with CFDA number 47.083 - Integrative Activities, will support research to improve understanding of how osteocytes (strain-sensing cells embedded in bone tissue) regulate bone material properties and fracture resistance. The $342,516 award to Montana State University, with a period of performance from Sep 1, 2024 to Aug 31, 2029, will pursue two main objectives: 1) determining the impacts of direct...
This National Science Foundation (NSF) Career award, under the Mathematical and Physical Sciences (CFDA 47.049) program, aims to develop a novel magnetoelectric biomaterial that can replicate the microstructures and physical stimuli of natural human bones. The $113,932 project, awarded to Boise State University on January 15, 2025, will focus on three key objectives: (1) 3D printing of magnetoelectric bioscaffolds mimicking the porous structure and mechanical properties of bones, (2)...
This Project Grant award of $456,085, awarded by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), supports a highly interdisciplinary research project to study the effects of aging on the responsiveness of osteocytes (bone cells) to mechanical loading. The project aims to develop multiplexed imaging models to predict osteocyte activation in response to altered mechanical loads, create macro and micro-level 3D finite element and fluid-structure interaction...
The National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation awarded Montana State University a $413,072 Project Grant under the Engineering (CFDA 47.041) federal grant program.
The grant will fund collaborative research to determine the impacts of lacunar-canalicular remodeling on bone fracture toughness. Montana State University will lead the research as the awardee, working with partners to examine bone microstructure changes at the cellular level and their...