Project Grant 2338915
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $750,000.00 will investigate how the central nervous system of vertebrates produces coordinated leg movements. Specifically, the project will use the turtle spinal cord as a model system to pharmacologically perturb inhibitory and excitatory neurotransmitter receptors to understand how the spinal cord generates and selects appropriate motor outputs for swimming, scratching, and leg withdrawal...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke awarded a $2.89 million Project Grant on September 5, 2025, to the University of Colorado-Denver under the Drug Use and Addiction Research Programs (CFDA 93.279) to conduct a comprehensive five-year research initiative examining cannabis use impact on pain and recovery following total knee arthroplasty (TKA). The project employs an integrated multidisciplinary approach combining basic and clinical science...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will provide $350,000 to Creighton University to investigate the effects of environmental enrichment on the abuse liability of minor cannabinoids such as delta-8-THC and CBD. The research aims to determine if adolescent exposure to high- or low-novelty environments can alter sensitivity to these cannabis compounds using animal models....
- This $241,401 Project Grant, awarded by the National Science Foundation (NSF) under the Engineering (CFDA 47.041) program, supports the development of in vitro models to better understand the mechanisms driving chronic pain and identify new treatment targets. Specifically, the award will fund the engineering of a physiologically-relevant multi-compartment model of nociceptor hypersensitivity and the establishment of a neuroimmune-specific model to test anti-inflammatory macrophage mechanisms...
- Federal Grant Award Summary Washington State University received a $153,000 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) beginning June 15, 2025, and concluding May 31, 2027. The award supports a six-month longitudinal research study examining the relationship between naturalistic cannabis use and daily functioning in young adults with chronic pain using an innovative ecological momentary assessment burst...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Pennsylvania a Project Grant totaling $667,349 (awarded August 1, 2025, with completion targeted for June 30, 2030) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This research grant supports a neuroscience investigation into state-dependent control of nociception (pain sensation) in opioid circuits,...
- The National Science Foundation (NSF) awarded a $253,890 Project Grant under the Biological Sciences program (CFDA 47.074) to Western University of Health Sciences to conduct research on sensory membrane proteins. The goal is to develop computational tools capable of realistic simulations of how these proteins respond to external stimuli like pressure, heat, and sound. The research project, titled "Collaborative Research: Ultra-Fast Simulations of Sensory Membrane Proteins with Validation...
- Federal Project Grant Award Summary Middlebury College received a $540,427 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279) effective August 18, 2025, with completion targeted for June 30, 2028. The award supports research to develop biologically-motivated mathematical models that explain mechanisms of interindividual variation in pain modulation through spinal cord stimulation (SCS). The...
- Federal Project Grant Award Summary Harris-Stowe State University received a $224,000 Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859) effective September 1, 2025, through August 31, 2029. The project, titled "The Genetics of Cannabinoid Signaling: An Organismal Analysis," seeks to elucidate the molecular-genetic mechanisms by which cannabidiol (CBD) produces therapeutic effects for...
- Federal Grant Award Summary The University of South Dakota received a $444,570 Project Grant from the National Science Foundation (NSF) Division of Environmental Biology under the Biological Sciences program (CFDA 47.074), awarded January 1, 2026 and concluding December 31, 2028. This collaborative research initiative examines the mechanisms driving continental-scale patterns of size spectra in freshwater streams by leveraging the National Ecological Observatory Network (NEON) infrastructure....
The National Science Foundation (NSF) awarded a $750,000 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of South Dakota. The grant, awarded from July 1, 2024 to June 30, 2027, will support research to understand the dual pain-increasing and pain-decreasing effects of the endocannabinoid system in the medicinal leech Hirudo verbana. The project aims to examine the neuronal mechanisms by which different patterns of neural activity can trigger pro- versus anti-nociceptive effects mediated by endocannabinoids. This comparative model using the leech, which shares the same endocannabinoid signaling molecules as humans, is expected to provide valuable insights into the modulation of pain. The grant will also provide mentoring and training opportunities in STEM fields to promote the inclusion of underrepresented groups. No subawards are planned under this award.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $750.0k | 7/2/24 |