This $200,000 Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support research by The Research Foundation for the State University of New York (RF SUNY) to investigate the genetic basis of chemosensory behavior in the roundworm Caenorhabditis elegans. The project aims to understand how genetic diversity and environmental factors influence how C. elegans interacts with its surroundings, which is crucial for the animal's survival....
This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Carleton College that will investigate how neurons develop and form circuits that regulate reproductive behaviors in the model organism C. elegans. The $419,182 award, effective September 1, 2024 through August 31, 2027, aims to elucidate the molecular mechanisms that integrate sex-determining signals with neurodevelopmental processes. The research will leverage...
This Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), provides $300,000 to the University of Kansas Center for Research Inc. from February 1, 2023 to January 31, 2025. The award will support research investigating delivery and trafficking of DNA introduced to cells from environmental sources using the genetically tractable organism Caenorhabditis elegans. The project aims to gain new...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $1,000,000 to the University of Michigan provides funding from August 1, 2024 to July 31, 2028 to study the molecular mechanism of telomere maintenance in the model organism Caenorhabditis elegans. The research aims to leverage the simplicity of the worm's shelterin protein complex to answer fundamental questions about the structure and function of these proteins in chromosome end protection and...
The University of Missouri System was awarded a $624,059 Project Grant from the National Science Foundation Division of Integrative Organismal Systems. The grant falls under the Biological Sciences program (CFDA 47.074) to support research elucidating the mechanisms of nematode disease resistance mediated by serine hydroxymethyltransferase from November 1, 2021 to October 31, 2025. The Biological Sciences program aims to advance the field and strengthen the national scientific enterprise by...
This $1,000,000 Project Grant awarded by the National Science Foundation (NSF) Division of Integrative Organismal Systems supports research to examine the genetic and molecular changes that have enabled self-fertility to evolve in two different nematode (worm) species, Caenorhabditis elegans and C. briggsae. The key objectives are to reconstruct the evolutionary steps that allowed specific regulatory proteins (FOG-2 and SHE-1) to emerge from related gene families and become essential...
The National Science Foundation awarded Wabash College a $466,738 Project Grant under the Biological Sciences program (CFDA 47.074) to develop a novel protein control system in the nematode Caenorhabditis elegans. The college will engineer a nematode-optimized degradron-latching orthogonal cage/key protein system called NEMDEGRONLOCKR to enable targeted degradation of regulatory proteins. Researchers will computationally design, biophysically test, and apply CRISPR-CAS9 to fuse NEMDEGRONLOCKR to...
The National Science Foundation (NSF) awarded a Project Grant under the Biological Sciences (CFDA 47.074) program to investigate the developmental genetic and environmental factors influencing segment addition in annelid worms. The $270,000 award, effective from October 1, 2025 to September 30, 2028, supports a postdoctoral research fellowship. The project aims to identify the genetic program responsible for annelid segmentation and examine how resource availability impacts juvenile segment...
This $360,000 Project Grant award, provided by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) program, aims to investigate the role of neuron-neuron communication in the post-mitotic maturation of neurons during postnatal development. Utilizing the model organism Caenorhabditis elegans, the research will leverage advanced genetics, behavioral assays, microscopy, and genomics tools to examine the molecular and functional maturation of neurons. The project...
This Project Grant award, funded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports a postdoctoral research fellowship investigating the role of phenotypic plasticity in enabling population persistence in novel environments. The $240,000 award, spanning 3 years from September 2025 to August 2028, will fund a genomic analysis of the model organism Caenorhabditis elegans to characterize the mechanisms of environmental assessment and how they vary across...