This $291,710 Project Grant awarded by the National Science Foundation (NSF) under the Biological Sciences (CFDA 47.074) program supports an integrative structural and functional study to dissect the regulatory mechanisms of ciliary motility. The project aims to enhance the understanding of motile cilia and flagella, cellular structures responsible for the locomotion of many single-celled eukaryotes and the movement of fluids in multi-cellular organisms. The study will focus on investigating the...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $123,956 Project Grant to New Mexico State University (NMSU) through the Biological Sciences program (CFDA 47.074) to support a 3-year research project. The project will probe the role of the small GTPase Rap1 protein in the mechanisms that drive morphogenesis - the changes in cell and tissue shape and arrangement during development. The goals are for the Principal Investigator to learn and apply...
This $448,150 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) aims to develop a DNA-based toolbox for the rapid and precise modulation of cell membrane protein-protein interactions (PPIs). The goal is to establish a modular approach using antibodies and aptamers to enable targeted DNA barcoding of cell membrane proteins, particularly receptor tyrosine kinases. This will allow for the controlled stabilization of specific PPI pairs on living...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $1,004,927 Project Grant to The Johns Hopkins University from July 1, 2021 to June 30, 2025. The grant supports research titled "Probing Phosphorylation Events in Biological Membranes" under the Biological Sciences program (CFDA 47.074). The goal of the Biological Sciences program is to promote progress in the biological sciences and strengthen the nation's scientific enterprise by increasing...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded Scripps College a $923,538 Project Grant under the Biological Sciences program (CFDA 47.074) from July 15, 2021 through June 30, 2025. The grant funds research into the role of the haploidizer gene in genome elimination by a selfish B chromosome. The Biological Sciences program aims to advance the field and strengthen the national scientific enterprise through basic biological research. This award supports...
This federal Project Grant award of $946,895 from the National Science Foundation's (NSF) Division of Molecular and Cellular Biosciences (CFDA 47.074 Biological Sciences) will fund research to advance the understanding of protein phosphorylation and its role in coordinating cell division. The project aims to identify new enzymes that carry out phosphorylation and the substrate proteins they modify to ensure proper cell division. Researchers will employ computational, biochemical, proteomic,...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $1,068,821 Project Grant to the University of Pittsburgh for the project "Collaborative Research: Alpha-Arrestins' Impact on Cellular Physiology." This research, conducted under the NSF Biological Sciences program (CFDA 47.074), focuses on understanding how a class of proteins called alpha-arrestins regulate nutrient transporters to maintain metabolite balance and mitochondrial function in...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $293,514 Project Grant to The Trustees of Trinity College in Hartford, Connecticut. The grant supports research from September 1, 2021 to August 31, 2024 under the Biological Sciences program (CFDA 47.074). The grant funds development of microelectrophoretic and statistical tools to study kinase- and reactive oxygen species-based signaling pathways in the social amoeba Dictyostelium discoideum. The...
This $476,910 project grant from the National Science Foundation's Division of Integrative Organismal Systems and Biological Sciences program (CFDA 47.074) supports research examining light signaling in marine photosynthetic organisms. Specifically, the grantee Southern Methodist University will investigate the function of blue light sensing proteins called aureochromes that are widely distributed in marine algae. The university will study the photochemical kinetics, expression patterns, and...
The National Science Foundation (NSF) awarded a $626,831 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Wisconsin-Milwaukee (UWM) to conduct collaborative research on the molecular mechanisms behind how certain bacteria use light-sensing proteins called phytochromes to regulate essential developmental processes. The project aims to use advanced structural biology techniques like cryo-electron microscopy and time-resolved X-ray crystallography to study...