The National Science Foundation (NSF) Directorate for Mathematical and Physical Sciences awarded a $399,755 Project Grant to the University of California, Santa Barbara (UCSB) under the Mathematical and Physical Sciences program (CFDA 47.049). The grant funds the development of new mathematical modeling paradigms and simulation software tools for investigating cell mechanics across multiple scales. This includes contributions from cell membranes and the cytoskeleton, and the roles of geometry,...
This is a $260,138 federal Project Grant awarded by the National Science Foundation (NSF) under the Mathematical and Physical Sciences program (CFDA 47.049). The grant was awarded to Virginia Polytechnic Institute & State University (Virginia Tech) on September 1, 2024, with a projected completion date of August 31, 2027. The grant funds collaborative research to understand how variations in the molecular composition of lipids and sterols govern the material properties and emergent...
The National Science Foundation awarded a $409,795 Project Grant to the University of Houston System under the Engineering federal grant program (CFDA 47.041) to support fundamental research on the mechanics of active biological membranes from May 1, 2023 to April 30, 2026. The research aims to establish a rigorous theoretical framework integrating continuum mechanics and non-equilibrium statistical mechanics to model active membranes. Specifically, the university will focus on entropic...
This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award of $342,318 supports research at the University of Wisconsin - Madison to develop a novel theoretical and computational framework for modeling the mechanical deformation and interactions of biomembranes with transport and electrochemical processes. The 3-year research project, starting on Sep 1, 2024, aims to create an open-source computational tool to model key biomembrane phenomena like endocytosis,...
This $208,784 federal Project Grant award from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project to study the emergent dynamics and scaling laws of bioinspired lipid membranes. The University of Arizona, as the primary awardee, will integrate experimental methods such as neutron spectroscopy, NMR, and flicker spectroscopy with molecular dynamics simulations. This integrated approach aims to establish the...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded Virginia Polytechnic Institute and State University a $297,204 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) for the period of August 1, 2021 through July 31, 2023. The grant funds research titled "EAGER: TOPOGRAPHICALLY INDUCED LATERAL ORGANIZATION IN BIOMIMETIC LIPID MEMBRANES" to promote progress in the biological sciences and increase understanding of major...
This federal Project Grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports research to quantify the mechanical forces inside living cells and determine how changes in these forces impact cellular behavior. The $160,000 award to Boise State University, with a project period from February 1, 2025 to January 31, 2028, aims to develop predictive tools that use mechanical forces to control cell behavior, enabling advances in tissue engineering,...
This federal Project Grant award of $600,000 from the National Science Foundation's (NSF) Mathematical and Physical Sciences Program (CFDA 47.049) supports research by Markus Deserno of Carnegie Mellon University to investigate how the asymmetry of cell membranes affects the phase behavior of their lipid constituents. The research aims to develop theoretical and computational techniques to elucidate how factors like differential stress and cholesterol partitioning impact lipid mixing in...
The National Science Foundation awarded a $890,510 project grant to Virginia Commonwealth University under the Engineering federal grant program (CFDA 47.041) for research titled "BIOMECHANICS OF LEADER CELLS." The five-year award, issued February 1, 2022 with a completion date of January 31, 2027, will support research into the biomechanics of leader cells. The NSF's Engineering program seeks to improve quality of life and economic strength by fostering innovation and excellence in...
The National Science Foundation (NSF) awarded a $164,120 Project Grant to the University of Rochester under the Mathematical and Physical Sciences program (CFDA 47.049). The grant funds a collaborative research project between Professor Daniel Mittleman of Brown University and Professor Michael Ruggiero of the University of Vermont to study the vibrational motions of clathrate materials using terahertz spectroscopy. The goal is to investigate the fundamental kinetics and dynamics driving the...