Project Grant 2319786

Award Date 9/15/24
Completion Date 8/31/28
Dollars Obligated $252K
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Durham, NC 27705, USA
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This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $181,981 to the University of Washington (UW) to develop innovative tools and resources to enhance the use of sea urchins as research models. The key products and services to be delivered include: Establishing efficient protocols for culturing sea urchin cells to investigate gene function in vitro. Enabling rapid, scalable DNA transfection of sea urchin embryos, adult tissues,...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award of $688,676 aims to develop new tools and resources to enhance the use of sea urchins as a research model organism. The key products and services being delivered include: Protocols for efficiently culturing sea urchin cells to investigate gene function in vitro. Techniques for rapid, scalable DNA transfection of sea urchin embryos, adult tissues, and cell cultures to enable conditional and reversible...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award provides $795,209 to Brown University to create the next generation of tools to enhance the utility of sea urchins as research models. The overarching goals of this 4-year project are to: 1) develop simple and efficient protocols for culturing cells from sea urchin embryos to investigate gene function in vitro; 2) enable rapid, scalable DNA transfection of embryos, adult tissues, and cell cultures for...
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This $251,573 federal project grant awarded by the National Science Foundation's Biological Sciences (CFDA 47.074) program aims to create the next generation of tools to enhance the utility of sea urchins as research models. The key products and services to be delivered under this 4-year award include:

  1. Developing simple and efficient protocols for culturing cells from sea urchin embryos to investigate gene function in vitro.
  2. Establishing rapid, scalable DNA transfection techniques for conditional and reversible gene control in sea urchin embryos, adult tissues, and cell cultures.
  3. Implementing techniques to promote standardization of sea urchin husbandry with open hardware and cryopreservation for sea urchin germplasm and cell lines.
  4. Creating virtual, interactive educational materials to reach secondary school and undergraduate students, as well as researchers, in the echinoderm research community.

These integrated technologies are intended to remove bottlenecks and provide scalable, sustainable resources to enable new avenues of investigation that fully leverage the valuable properties of echinoderms as research organisms. The award was made on Sep 15, 2024 to Duke University, a leading research institution with extensive expertise in federal grant management.

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