Project Grant 2319784

Award Date 9/15/24
Completion Date 8/31/28
Dollars Obligated $182K
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
Seattle, WA 98195, USA
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This $251,573 federal project grant awarded by the National Science Foundation's Biological Sciences (CFDA 47.074) program aims to create the next generation of tools to enhance the utility of sea urchins as research models. The key products and services to be delivered under this 4-year award include: Developing simple and efficient protocols for culturing cells from sea urchin embryos to investigate gene function in vitro. Establishing rapid, scalable DNA transfection techniques for...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award of $688,676 aims to develop new tools and resources to enhance the use of sea urchins as a research model organism. The key products and services being delivered include: Protocols for efficiently culturing sea urchin cells to investigate gene function in vitro. Techniques for rapid, scalable DNA transfection of sea urchin embryos, adult tissues, and cell cultures to enable conditional and reversible...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Project Grant award of $192,388 to the Gloucester Marine Genomics Institute (GMGI) will fund the development of innovative tools and resources to enhance the utility of sea urchins as a valuable research model organism. The key products and services to be delivered under this 4-year grant, which runs from September 2024 to August 2028, include: Establishing simple and efficient protocols for culturing sea urchin cells to...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award provides $795,209 to Brown University to create the next generation of tools to enhance the utility of sea urchins as research models. The overarching goals of this 4-year project are to: 1) develop simple and efficient protocols for culturing cells from sea urchin embryos to investigate gene function in vitro; 2) enable rapid, scalable DNA transfection of embryos, adult tissues, and cell cultures for...
This Project Grant award, valued at $415,782.00, was provided by the National Science Foundation's Geosciences Program (CFDA 47.050) to Baylor University. The funding will support research to study how the evolution of feeding structure morphology in sea urchins is influenced by functional performance, and how this performance impacts the long-term evolution and ecology of these animals. The researchers plan to create a publicly accessible online database of 3D digital scans of all known...
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The National Science Foundation awarded a $142,508 Project Grant to the California Academy of Sciences to support collaborative research integrating phylogenomics with the fossil record of sea urchins. The goal of this three-year award, running from April 2021 through March 2024, is to advance understanding of macroevolutionary patterns in sea urchins through integrating modern genomic techniques with the fossil record of this model clade. This award supports the Biological Sciences program's...
This Project Grant award, valued at $231,912, was provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) to the University of Washington (UW) to study the hydrodynamic consequences of spines on zooplankton, particularly barnacle nauplii larvae. The key objectives of this research project are to: (1) determine the functional consequences of the presence, location, and morphology of spines on hydrodynamic forces and torques; (2) examine the impacts of spines...
The University of California San Diego Scripps Institution of Oceanography was awarded a $673,107 Project Grant from the National Science Foundation under the Biological Sciences program (CFDA 47.074) for the period of April 15, 2021 through March 31, 2024. The grant funds collaborative research between the awardee and other institutions to integrate phylogenomics with the fossil record to advance macroevolutionary research using sea urchins as a model clade. The Biological Sciences program aims...

This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $181,981 to the University of Washington (UW) to develop innovative tools and resources to enhance the use of sea urchins as research models. The key products and services to be delivered include:

  1. Establishing efficient protocols for culturing sea urchin cells to investigate gene function in vitro.
  2. Enabling rapid, scalable DNA transfection of sea urchin embryos, adult tissues, and cell cultures for conditional and reversible gene control.
  3. Developing techniques to standardize sea urchin husbandry, including open hardware and cryopreservation for germplasm and cell lines.
  4. Creating virtual, interactive educational materials to engage secondary school, undergraduate students, and researchers in the echinoderm research community.

These integrated technologies will remove key bottlenecks and provide scalable resources to enable new areas of biological research using sea urchins as important model organisms. The project commences on September 15, 2024 and is scheduled for completion by August 31, 2028.

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