The National Science Foundation awarded $307,345 under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program to the University of Arizona to support collaborative research on programmable living materials through synthetic biofilm engineering and quantitative computational modeling. The University will develop bioengineering tools to control bacterial cell deposition and assembly into material blocks with distinct interfaces. Researchers will integrate synthetic cell-cell...
The National Science Foundation awarded a $548,102 project grant under the Engineering (47.041) program to the University of Texas at Austin to develop a predictive framework for understanding how bacteria sense and respond to surface mechanics upon attachment. The three-year award beginning April 1, 2022 will support research using atomic force microscopy, high-throughput culturing, finite element modeling, quantitative confocal microscopy, and genetic manipulation to characterize the stresses,...
This $265,007 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) will support collaborative research to advance the understanding of bacterial swimming motion. The research aims to leverage robophysical modeling techniques from robotics to realistically emulate and study the complex interplay of physical and biological factors governing bacterial motility behaviors. Key objectives include elucidating how fluid mechanical forces shape the ways...
This National Science Foundation (NSF) Project Grant award under CFDA Program 47.041 - Engineering, in the amount of $232,786, will support collaborative research on robophysical modeling of bacterial swimming motion. The project aims to advance the understanding of how fluid mechanical forces shape the ways bacteria navigate their complex environments and interact with each other. By adopting techniques of robophysical modeling, the researchers will isolate physical effects governing...
This $208,784 federal Project Grant award from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports a collaborative research project to study the emergent dynamics and scaling laws of bioinspired lipid membranes. The University of Arizona, as the primary awardee, will integrate experimental methods such as neutron spectroscopy, NMR, and flicker spectroscopy with molecular dynamics simulations. This integrated approach aims to establish the...
This $380,500 National Science Foundation project grant supports collaborative research at the University of California, Los Angeles to analyze mechanosensitive channels in bacteria using force spectroscopy. The research team will utilize atomic force microscopy to observe the opening of single mechanosensitive channels in living bacteria in response to mechanical compression. This will help characterize how these channels function to protect bacteria from rupturing due to excessive internal...
The National Science Foundation (NSF) awarded a $195,656 Project Grant under its Engineering program (CFDA 47.041) to the University of Cincinnati for a collaborative research study on the collective dynamics of multiple bacterial flagella. This 3-year project, starting on July 1, 2024, aims to understand how the flagellar filaments of peritrichous bacteria, such as E. coli, synchronize and rotate collectively to enable swimming in fluid media. The research will integrate macroscopic model...
This $383,799 National Science Foundation project grant supports collaborative research to map protein-membrane interactions across molecular to cellular scales. Funded under the Biological Sciences program (CFDA 47.074), the research aims to better understand how integral membrane proteins and surrounding phospholipid membranes work together to enable cellular processes. The University of Arizona will conduct multiscale modeling from molecular dynamics simulations of single protein-membrane...
The University of Arizona received a three-year, $215,000 Project Grant from the National Science Foundation Division of Electrical, Communications and Cyber Systems under the Engineering federal grant program (CFDA 47.041). The grant will support collaborative research on combined transport and scanning probe studies of twisted van der Waals devices through August 2024. As part of its mission to improve engineering innovation and education, the NSF Engineering program aims to foster...
This National Science Foundation (NSF) Engineering program (CFDA 47.041) grant award of $183,926 to the California Institute of Technology (Caltech) will investigate how bacteria move in porous environments such as tissue, gels, soils, and sediment. The project will use 3D printed porous media to study how the motion and self-organization of bacteria depend on the properties of their environment, the cells themselves, and interactions among the cells. This work will provide new experimental...