Project Grant 2305834
- The National Science Foundation (NSF) awarded a $435,914 Project Grant to The Ohio State University under the Chemistry Division's Chemical Structure, Dynamics & Mechanisms B program (CFDA 47.049 Mathematical and Physical Sciences). The grant supports the development of new classes of dinuclear transition metal complexes to study forbidden electron paramagnetic resonance (EPR) spectroscopic transitions. The goal is to understand how molecular structure can violate EPR selection rules to...
- This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program provides $410,939 to Clemson University to conduct research on the biophysical mechanisms of membrane protein folding and stability. The project will use advanced single-molecule force spectroscopy techniques, specifically atomic force microscopy, to study how membrane proteins interact with cell membranes and maintain their proper structure. The goal is to gain fundamental biophysical...
- Federal Project Grant Award Summary The University of Miami received a $501,165 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective April 1, 2026, through January 31, 2031. This award supports investigator-initiated research focused on determining the structures and dynamics of three critical human membrane proteins and their associated macromolecular complexes: connexin channels (which...
- The National Science Foundation (NSF) awarded a $253,890 Project Grant under the Biological Sciences program (CFDA 47.074) to Western University of Health Sciences to conduct research on sensory membrane proteins. The goal is to develop computational tools capable of realistic simulations of how these proteins respond to external stimuli like pressure, heat, and sound. The research project, titled "Collaborative Research: Ultra-Fast Simulations of Sensory Membrane Proteins with Validation...
- The National Science Foundation (NSF) Division of Chemistry awarded a 3-year, $389,999 Project Grant to Florida State University (FSU) under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new approaches to characterize the structural dynamics of proteins that play critical roles in chemical reactions within biological cells. The project, led by Dr. Christian Bleiholder, will combine and enhance the capabilities of tandem-ion mobility spectrometry coupled with mass...
- This $659,728 federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will support the development of the BioMemBHub cyberinfrastructure. BioMemBHub is designed to advance modeling and analysis capabilities for biomembranes, proteins, peptides, and small molecules. The project will create an integrated platform consisting of seven web servers and three large databases to enable exploration of the structural and dynamic aspects of...
- This $534,974 Project Grant awarded by the National Science Foundation (NSF) Division of Chemistry supports the development of native-like peptoid macrodiscs and advanced solid-state nuclear magnetic resonance (NMR) methods for structural studies of membrane proteins. The principal investigator, Professor Alexander Nevzorov and his research group at North Carolina State University (NC State), are designing synthetic lipid-based membrane systems to enable high-resolution NMR spectroscopy of these...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $1,050,082 Project Grant to the University of Pittsburgh to support research titled "The Virtues of Lanthanides and Fluorine for Tracking In-Cell Protein Conformation: A Marriage of NMR and EPR" from June 1, 2021 to May 31, 2025. This Project Grant funding will support research under the Biological Sciences federal grant program (CFDA 47.074) to advance understanding of major biological problems....
- Federal Grant Award Summary Miami University received a $763,232 Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective June 1, 2026 through May 31, 2029. The award funds research to identify the principles governing gene regulatory network evolution using beetle wing morphology as a model system. The primary research product involves determining whether gene network evolution...
- This three-year, $525,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports coordinated mechanistic approaches to desulfonation in two-component FMN monooxygenases. East Carolina University will deliver structural investigations of alkane sulfonate monooxygenase systems through X-ray crystallography and analysis, with the University of Massachusetts Boston performing the crystallography work. Quantum mechanical calculations...
The National Science Foundation (NSF) awarded a $577,656 Project Grant to Miami University to investigate the structural and dynamic properties of two membrane proteins, Pinholin and gp28, using electron paramagnetic resonance (EPR) spectroscopic techniques. The grant, funded through NSF's Mathematical and Physical Sciences (CFDA 47.049) program, will enable Professor Gary A. Lorigan and his team to elucidate the secondary and tertiary structure of these membrane-bound proteins and develop structural models to better understand their mechanisms of action. The project will provide valuable research experience for graduate and undergraduate students at Miami University, preparing them for careers in biophysical chemistry. No sub-awards are planned under this grant, which has an award date of September 15, 2023, and an ultimate completion date of August 31, 2026.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $577.7k | 9/12/23 |