The National Science Foundation awarded a three-year $400,000 project grant to the University of Rochester under the Mathematical and Physical Sciences program (CFDA 47.049). The grant supports collaborative research between the University of Rochester, New Jersey Institute of Technology, and University of Virginia to investigate the supramolecular assembly of beta-sheet nanofibrils composed of mirror-image peptides. The team will determine the structure of these systems with near-atomic...
Under this $200,000 Project Grant from the National Science Foundation Division of Chemistry's Mathematical and Physical Sciences program (CFDA 47.049), the New Jersey Institute of Technology will collaborate with the University of Rochester and University of Virginia to investigate the supramolecular assembly of beta-sheet nanofibrils composed of mirror-image peptides. The collaborative team will determine the structure of these systems with near-atomic precision using cryo-electron...
The University of Virginia will receive $372,379 over three years from the National Science Foundation Division of Materials Research under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to support the project "Engineering the Design of Self-Assembling, Shear-Thinning Pentapeptide Hydrogels to Promote Neural Cell Growth and Differentiation." The university will conduct research to engineer hydrogel materials using pentapeptide molecules that can...
The University of Virginia received a $483,000 Project Grant award from the National Science Foundation Division of Chemistry under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to develop new enantioselective fluorescent sensors for amino acids. Professor Lin Pu and researchers will further optimize a 1,1'-binaphthyl-coumarin-based fluorescent probe and its pseudo-enantiomer to simultaneously determine the concentration and enantiomeric composition of amino acid...
This Project Grant award from the National Science Foundation's (CFDA 47.049 - Mathematical and Physical Sciences) supports computational and theoretical research aimed at designing peptide-functionalized surfaces with tunable nanoscale patterns. The goal is to understand how molecules change their behaviors when tethered to a surface and how these molecular behaviors control surface interactions with water. The research project will couple molecular dynamics simulations with deep learning...
This Project Grant award from the National Science Foundation's (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) Federal Grant Program provides $451,460 to Emory University to conduct collaborative research on the computational design of peptide-based filamentous nanomaterials. The project, led by researchers from Emory University and the University of Illinois Chicago, aims to develop a general scientific approach to computation-guided design of...
This $600,000 Project Grant award, provided by the National Science Foundation's (NSF) Engineering program (CFDA 47.041), will support research at the University of Virginia (UVA) to design innovative, biology-inspired adsorptive separation materials using peptides to purify new protein-based therapeutic medicines from contaminants. The project aims to advance the molecular understanding of protein adsorption behaviors and establish design rules for mixed-mode peptide ligands to enable efficient...
This Project Grant award from the National Science Foundation's Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) program supports a collaborative research effort led by Emory University and the University of Illinois Chicago to design and develop peptide-based filamentous nanomaterials. The $300,000 award, effective from August 1, 2024 to July 31, 2027, will leverage computational methods to systematically explore the energetics and structural designability of...
The National Science Foundation awarded a $410,440 Project Grant to the University of Virginia under the Mathematical and Physical Sciences program (CFDA 47.049). The grant funds an Research Experiences for Undergraduates Site focused on advanced materials synthesis from September 2021 through August 2024. As part of the Mathematical and Physical Sciences program's goals to strengthen the nation's scientific enterprise and increase knowledge of major problems, this REU Site will provide research...
This three-year, $398,548 project grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research between the College of William and Mary and Old Dominion University to study the intrinsic gas-phase acid-base properties and structures of non-protein amino acids and peptides containing these amino acids. The research teams, led by John C. Poutsma of William and Mary and Jennifer Poutsma of Old Dominion University, will employ...