Project Grant 2154537
- This three-year, $101,452 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program will support collaborative research between Old Dominion University and the College of William & Mary on the intrinsic gas-phase acid-base properties and structures of non-protein amino acids and peptides. The research teams, led by Drs. John and Jennifer Poutsma, will utilize mass spectrometry experiments and computational modeling to study how substituting...
- This National Science Foundation (NSF) Project Grant award under the Mathematical and Physical Sciences program (CFDA 47.049) provides $343,638 to Texas A&M University-Commerce to conduct research on the thermochemistry, reaction dynamics, and conformational changes associated with the collisional activation of peptide ternary complexes and recombinant tagged proteins. The key products and services to be delivered through this 3-year grant include: Developing new zinc- and nickel-binding...
- The University of Virginia, as prime grantee, was awarded a three-year project grant of $199,999 by the National Science Foundation Division of Chemistry under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) to investigate the supramolecular assembly of beta-sheet nanofibrils composed of mirror-image peptides. Working with sub-grantees the University of Rochester and New Jersey Institute of Technology, the University of Virginia will determine the near-atomic structure...
- The National Science Foundation, through its Division of Chemistry and the Mathematical and Physical Sciences program (CFDA 47.049), awarded a $577,690 Project Grant to the University of North Carolina at Chapel Hill from July 1, 2023 through June 30, 2027. The grant supports research to characterize the biosynthetic pathways of dehydroamino acids in nonribosomal peptides, which are biologically and industrially important natural products. The research aims to understand the molecular details of...
- This National Science Foundation Project Grant of $249,990 will support research into innovative structural characterization of biomolecular ions through mass spectrometry and infrared action spectroscopy. Funded under the Mathematical and Physical Sciences program (CFDA 47.049), Professor Daniel Thomas and students at the University of Rhode Island will study peptide and RNA chain folding properties by cooling samples in helium nanodroplets and analyzing infrared light absorption. Outreach...
- This three-year $525,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports research into the structure, dynamics, and transport properties of charged macromolecular systems in aqueous solutions. The grantee, University of Massachusetts at Amherst, will investigate the hierarchical organization and non-diffusive dynamics of polyzwitterions, as well as forces controlling coacervate gel composite formation and phase behavior,...
- Under this $200,000 Project Grant from the National Science Foundation Division of Chemistry's Mathematical and Physical Sciences program (CFDA 47.049), the New Jersey Institute of Technology will collaborate with the University of Rochester and University of Virginia to investigate the supramolecular assembly of beta-sheet nanofibrils composed of mirror-image peptides. The collaborative team will determine the structure of these systems with near-atomic precision using cryo-electron...
- The National Science Foundation awarded a three-year $400,000 project grant to the University of Rochester under the Mathematical and Physical Sciences program (CFDA 47.049). The grant supports collaborative research between the University of Rochester, New Jersey Institute of Technology, and University of Virginia to investigate the supramolecular assembly of beta-sheet nanofibrils composed of mirror-image peptides. The team will determine the structure of these systems with near-atomic...
- The National Science Foundation (NSF) Division of Chemistry awarded a 3-year, $389,999 Project Grant to Florida State University (FSU) under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new approaches to characterize the structural dynamics of proteins that play critical roles in chemical reactions within biological cells. The project, led by Dr. Christian Bleiholder, will combine and enhance the capabilities of tandem-ion mobility spectrometry coupled with mass...
- The University of Utah will use a $550,000 Project Grant from the National Science Foundation Division of Chemistry to examine thermochemistry of metal-ligand bonds and protonated peptides from June 15, 2023 to May 31, 2026. The work falls under the NSF Mathematical and Physical Sciences program (CFDA 47.049), which aims to advance scientific knowledge and understanding in these fields. Professor Peter B. Armentrout and his research group will utilize guided ion beam tandem mass spectrometry...
This three-year, $398,548 project grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research between the College of William and Mary and Old Dominion University to study the intrinsic gas-phase acid-base properties and structures of non-protein amino acids and peptides containing these amino acids. The research teams, led by John C. Poutsma of William and Mary and Jennifer Poutsma of Old Dominion University, will employ mass spectrometry experiments and computational modeling to further understanding of how peptide structure relates to behavior during mass spectrometry analysis. Insights gained from systematically substituting non-proteinogenic amino acids into peptides could enhance peptide sequencing algorithms applied in proteomics. The majority of outlined projects will involve undergraduate research training to develop students' scientific skills.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $199.3k | 6/24/22 |