Project Grant 2302101
- This Project Grant from the National Science Foundation's Division of Human Resource Development provides $299,835 to Winston-Salem State University under the STEM Education program (CFDA 47.076) from August 2022 through July 2025. The university will use this funding to support faculty and undergraduate research investigating perfluoroalkyl substances (PFAS), a class of commonly used environmental toxins. Specifically, the researchers will conduct a comprehensive analysis using various...
- The National Science Foundation's STEM Education program awarded a $299,997 Project Grant to Winston-Salem State University (WSSU) to support research aimed at identifying latent frailty profiles in African American adults with prediabetes and diabetes. This three-year award will fund a series of secondary data analyses using the Jackson Heart Study public data resources to examine frailty in this population. The project has three main goals: 1) conduct basic research in latent profile...
- This $405,813 Project Grant award from the National Science Foundation (NSF) Integrative Activities (IA) program (CFDA 47.083) will support Professor Sezgin Kiren of Winston-Salem State University (WSSU) in studying the synthesis of complex organic molecules from the oxidation of pyrrole precursors. The research aims to develop novel cyclic imides and lactams, which have potential applications in pharmaceuticals and materials science but have been traditionally difficult to access. The project...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $502,940 to James Madison University (JMU) is funding research to investigate the molecular mechanisms underlying the relationship between tissue fibrosis and angiogenesis following injury. The research aims to elucidate how the sphingosine 1-phosphate (S1P) and cyclooxygenase-2 (COX-2) pathways mediate the crosstalk between these two critical tissue repair and regeneration processes. The...
- This $899,894 Project Grant award from the National Science Foundation's (NSF) Integrative Activities (IA) program, CFDA 47.083, will support research to characterize the structure, membrane topology, substrate specificity, and biochemical properties of a unique mitochondrial HAD phosphatase enzyme in a divergent unicellular organism. The project aims to elucidate the dual functional roles of this enzyme, which may provide insights into the broader cellular functions of the related TIM50 protein...
- This $999,996 Project Grant award, provided by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports fundamental research aimed at generating "designer mitochondria" for biotechnology, healthcare, and basic research applications. The key objectives are to identify the factors required for human mitochondrial DNA (mtDNA) replication and characterize the mechanisms underlying the species-specificity of this process. This work represents a critical step...
- Grant Award Summary North Dakota State University received a $570,477 CAREER Project Grant from the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), effective July 1, 2026 through June 30, 2031. The award supports fundamental research investigating how misplaced DNA and RNA inside cardiomyocytes (heart cells) alter cellular electrical activity and influence innate immune responses. The research will employ...
- This $715,500 federal Project Grant awarded by the National Science Foundation's (NSF) Engineering program will support research at the University of Illinois to investigate the relationship between exercise and cognitive health. The project aims to determine how muscle contraction during exercise may influence the activity and growth of cells in the hippocampus, the part of the brain involved in memory and learning. The research will conduct in vitro experiments culturing mouse muscle and...
- This $369,599 Project Grant award, funded by the National Science Foundation's Division of Mathematical Sciences (CFDA 47.049) and awarded June 15, 2025, supports intensive research in graph theory conducted through a partnership between Winston-Salem State University (WSSU), a historically Black university, and the American Institute of Mathematics (AIM). The award funds research focused on zero forcing—an iterative graph coloring process—and its variants, with applications to graph...
- This Project Grant award from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) provides $949,958 in funding to Rutgers, The State University of New Jersey, Camden Division to conduct research on the role of inorganic polyphosphate (polyP) in regulating mitochondrial physiology in mammals. The project aims to elucidate the molecular mechanisms by which polyP influences mitochondrial bioenergetics in normal and...
This $970,384 Project Grant award from the National Science Foundation (NSF) Integrative Activities (IA) program (CFDA 47.083) supports research at Winston-Salem State University (WSSU), a historically Black college and university, to investigate the role of mitochondrial damage-associated molecular patterns (mtDAMPs) in driving sterile inflammation following muscle contraction-induced injury. The key objectives are to elucidate the molecular mechanisms by which mtDAMPs mediate the inflammatory response to exercise-induced tissue trauma, and to enhance STEM research capacity and training at WSSU. The 3-year project will measure mitochondrial protein and nucleic acid levels, conduct in vitro studies of muscle-immune cell interactions, and determine the structural properties of a specific mtDAMP protein. This research seeks to provide insights into the similarities between clinical non-infectious trauma and the inflammatory response triggered by strenuous exercise. The award includes plans for sub-awards to support the research activities.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $49.9k | 11/22/23 | ||
| Not listed | $920.5k | 8/18/23 |