Project Grant 2247938
- The University of Chicago was awarded a $625,000 Project Grant from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences CFDA program. This three-year collaborative research project will elucidate the molecular mechanisms underlying the activation of ROBO receptor proteins that guide the growth and navigation of axons during neural circuit development. The research aims to determine how ROBO receptors have evolved to allow for the...
- Brown University was awarded a $947,500 Project Grant from the National Science Foundation Division of Integrative Organismal Systems. The grant falls under the Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the Nation's scientific enterprise through increasing scientific knowledge and enhancing understanding of major problems confronting the Nation. Specifically, the three-year grant will fund research from January 2021 to...
- This Project Grant award, funded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074), supports research at Brown University to investigate the evolutionary mechanisms underlying the diversity of life on Earth. The research focuses on analyzing changes in the developmental programs of echinoderms, such as sea urchins and sea stars, to understand how unique cell types like micromeres evolved and their potential role in species divergence. The $1,337,703 award...
- This NSF/BIO-UKRI/BBSRC Project Grant, awarded under the National Science Foundation's Biological Sciences program (CFDA 47.074), provides $1,012,160 to Brown University to create computational tools that integrate molecular data with structural brain imaging. The project aims to build a comprehensive 3D molecular and structural map of brain areas for olfaction in mice, an important model system for understanding neural circuits. By combining advanced imaging methods with spatial...
- This Project Grant from the National Science Foundation's Division of Integrative Organismal Systems provides $182,156 to Roger Williams University under the Biological Sciences program (CFDA 47.074) from September 1, 2021 through August 31, 2024. The funding supports collaborative research on the functional design of siphophore propulsion and behavior. The Biological Sciences program aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through...
- This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) project grant award to Brown University provides $380,480.00 in funding from February 1, 2025 to January 31, 2028 to investigate the neural control of elaborate gestural displays in animals, with a focus on woodpecker drumming behavior. The project aims to uncover the underlying brain mechanisms that enable the production and perception of these complex communication signals, with the long-term goal of advancing...
- This federal Project Grant award, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research to investigate the molecular mechanism of the VASA protein's role in regulating localized mRNA translation on the mitotic spindle during embryonic development. The $438,625 award to Brown University, spanning from August 1, 2025 to May 31, 2030, aims to: 1) identify VASA's target mRNAs and their...
- This Project Grant awarded by the National Science Foundation (NSF) Biological Sciences Program (CFDA 47.074) will support research to investigate the biochemical mechanisms that regulate receptor tyrosine kinase (RTK) proteins and their impact on the development of brain circuits controlling social and emotional behaviors. The $600,000 award, spanning 2025-2027, will be conducted by Children's Hospital Los Angeles, a prominent pediatric academic medical center and research institution. The...
- This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $1,000,000 in funding to Tufts University to study how a factor secreted from muscle regulates levels of neurotransmitter receptors in neurons that control movement in the roundworm Caenorhabditis elegans. The research aims to advance scientific understanding of how muscle releases factors that signal to the brain to control communication between neurons, which may provide...
- This Project Grant from the National Science Foundation's Division of Integrative Organismal Systems provides $223,850 to Providence College from September 1, 2021 through August 31, 2024. The funding supports collaborative research on the functional design of siphonophore propulsion and behavior under the Biological Sciences program (CFDA 47.074). The Biological Sciences program aims to promote progress in the biological sciences and strengthen the Nation's scientific enterprise through...
This National Science Foundation Project Grant award under the Biological Sciences program (CFDA 47.074) for $625,000 provides funding to Brown University from August 1, 2023 to July 31, 2026 to conduct collaborative research on the evolution of ligand-dependent Robo receptor activation mechanisms for axon guidance. The research aims to elucidate the molecular mechanisms underlying the activation of Robo family proteins, which control the growth and guidance of axons during neural circuit assembly in embryonic development. The project will integrate expertise in structural/biophysical and functional/genetic approaches to investigate Robo signaling and evolution, using ancient sequence reconstruction, biochemical methods, and axon guidance assays. The research has the potential to improve understanding of nervous system miswiring disorders and inform therapeutic approaches for neural circuit repair. The grant will also provide training opportunities for undergraduate and graduate students, with a focus on the career development of women and underrepresented minorities, and includes outreach activities at local high schools.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $625.0k | 7/16/23 |