Project Grant 2239639
Award Date
8/15/22
Completion Date
11/30/22
Dollars Obligated
$293K
Federal Agency
Division of Molecular and Cellular Biosciences
Federal Grant Program
47.074
Assistance Type
Project Grant
Place of Performance
University City, MO 63130, USA
Similar Awards
This $804,525 project grant from the National Science Foundation's Division of Molecular and Cellular Biosciences, under the Biological Sciences program (CFDA 47.074), will fund research exploring the epigenetic mechanisms by which ultraviolet B radiation alters DNA methylation patterns in plants. Specifically, the University of Missouri-St. Louis will investigate how UVB exposure and its photoreceptor interact to change locus- and tissue-specific DNA methylation in Arabidopsis thaliana, and how...
This $999,999 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research at the Donald Danforth Plant Science Center to elucidate the mechanisms initiating de novo chromatin modification cycles in plant cells. Over three years, the award will support experiments using cutting-edge techniques to dissect the molecular triggers establishing heritable DNA methylation patterns and long-term epigenetic silencing of transposable elements and...
This Project Grant award from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) Federal Grant Program provides $900,000 to The Regents of the University of Colorado (CU) to conduct research on the molecular mechanisms underlying the DNA methyltransferase 1 (DNMT1) enzyme's role in inheritance of gene silencing. The project aims to utilize structural biology, biochemistry, and cell biology methods to understand DNMT1 regulation and the mechanism cells use to restrict DNMT1...
This National Science Foundation (NSF) Project Grant award under the Biological Sciences (CFDA 47.074) program provides $796,823 to the University of Missouri System to conduct research on the "Genetic and Molecular Dissection of Meiotic Silencing by Unpaired DNA" over a 3-year period from March 2025 to February 2028. The research aims to better understand the mechanism behind the "meiotic silencing by unpaired DNA" (MSUD) pathway, which is a defense system that organisms use...
This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) Federal Grant Program will provide $950,000 to Texas A&M University from June 1, 2025 to May 31, 2029. The project will investigate how the enzyme thymine DNA glycosylase, a key player in the DNA demethylation pathway, is targeted to specific methyl groups throughout the genome. This research aims to improve understanding of how DNA methylation landscapes are established and maintained under...
This National Science Foundation project grant of $610,097 will fund the development of computational tools for analyzing and interpreting DNA methylation under the Biological Sciences program (CFDA 47.074). Awarded to Rice University on March 1, 2022 with a projected completion date of February 28, 2027, this grant will result in a suite of new open-source software tools and databases to enable researchers to better analyze DNA methylation data across experimental technologies and tissue/cell...
This National Science Foundation project grant award of $240,000 provides funding from July 1, 2024 through June 30, 2027 to support research investigating methylation and microbes as moderators of genotype-by-environment interactions. The award is made under the Biological Sciences program (CFDA 47.074) to promote progress in the biological sciences. The fellow will conduct integrative research using a grasshopper system to study how epigenetic changes to DNA structure and symbiotic...
The National Science Foundation awarded a three-year, $216,000 Project Grant to support research titled "Role of Transposable Elements and DNA Methylation on Immunity Gene Regulation and Diversification in Maize and Model Setaria viridis." The grant was awarded on September 1, 2021 with a completion date of August 31, 2024. The research is being conducted under the NSF's Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and...
The University of Georgia Research Foundation, Inc. received a $880,000 Project Grant award from the National Science Foundation Division of Molecular and Cellular Biosciences under the Biological Sciences federal grant program (CFDA 47.074). The three-year award running from July 1, 2023 to June 30, 2026 will support research investigating the mechanistic origins and evolution of gene body DNA methylation in plant models. Specifically, the grantee will explore the roles of histone...
The National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) awarded a $810,001 project grant to The Trustees of the University of Pennsylvania to study the role of N6-methyladenosine (m6A) modifications in regulating plant gene expression and response to bacterial pathogens. The 4-year project aims to characterize the addition and removal of m6A on plant RNAs and investigate how these epitranscriptomic processes impact a plant's ability to recognize and respond to...