Project Grant 2109697
- This $452,399 federal Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research at Hofstra University to investigate the epigenetic regulation of transposable elements in maize. The research aims to study the RNA-directed DNA methylation (RDDM) induced by naturally occurring maize "killer" alleles and explore the dynamic regulation of transposable element silencing in response to developmental cues. The project will...
- This $999,999 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) will fund research at the Donald Danforth Plant Science Center to elucidate the mechanisms initiating de novo chromatin modification cycles in plant cells. Over three years, the award will support experiments using cutting-edge techniques to dissect the molecular triggers establishing heritable DNA methylation patterns and long-term epigenetic silencing of transposable elements and...
- The National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) awarded a $810,001 project grant to The Trustees of the University of Pennsylvania to study the role of N6-methyladenosine (m6A) modifications in regulating plant gene expression and response to bacterial pathogens. The 4-year project aims to characterize the addition and removal of m6A on plant RNAs and investigate how these epitranscriptomic processes impact a plant's ability to recognize and respond to...
- This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $2,379,217 to the Donald Danforth Plant Science Center from March 1, 2022 to February 28, 2025. The grant supports research to develop targeted DNA integration techniques in plants. Specifically, the Center and its sub-awardees—the University of South Carolina Aiken Campus and University of Missouri—will work to engineer hyperactive versions of the Pong transposase proteins and...
- This $794,457 federal Project Grant award from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will support the development of new genetic analysis tools. The goal is to incorporate molecular and cellular biology knowledge, such as gene expression patterns and regulatory networks, directly into statistical models used to map genes, predict traits, and simulate changes in the genotype-to-phenotype relationships. The research will be conducted using simulated...
- This federal Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $796,823 to the University of Missouri System to conduct research on the genetic and molecular mechanisms behind meiotic silencing by unpaired DNA. The research aims to better understand how organisms use RNA-based gene silencing systems to identify and suppress the expression of DNA segments lacking a pairing partner, which can indicate the presence of viruses or...
- This National Science Foundation Project Grant award of $292,630 provides funding for "MOLECULAR DISSECTION OF ARABIDOPSIS DNA METHYLATION MECHANISM" research being conducted at the University of Missouri-St. Louis from August 15, 2022 through November 30, 2022. The research aims to further the understanding of how DNA methyltransferase enzymes locate specific sites for methylation modification in complex genomes like plants and mammals. This has implications for genome integrity and...
- This Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) provides $750,000 to the University of Missouri System from January 1, 2023 through December 31, 2026. The grant supports collaborative research among multiple institutions to elucidate the genetic and molecular mechanisms underlying nonhost resistance in plants. Nonhost resistance confers broad immunity to most plant species against pathogens that can infect other species. The research aims to...
- This National Science Foundation (NSF) Project Grant award under the Biological Sciences (CFDA 47.074) program provides funding of $993,190 to the University of Maine System to conduct research focused on engineering stable, transmissible plant minichromosomes for synthetic biology applications. The project, titled "NSF-DBT: PLANTSYNBIO: PLANT MINICHROMOSOME ENGINEERING", aims to develop methods that expand the limits of plant minichromosome size, structure, and composition to create a...
- The National Science Foundation (NSF) Division of Integrative Organismal Systems awarded a $277,978 Project Grant under the Biological Sciences program (CFDA 47.074) to the University of California, Berkeley. The 3-year grant, beginning on Sep 1, 2023, aims to develop new tools and resources to enable more efficient gene editing in maize, the world's most produced crop. Specifically, the project will generate maize lines that constitutively express the Cas9 gene editing enzyme and engineer...
The National Science Foundation awarded a three-year, $216,000 Project Grant to support research titled "Role of Transposable Elements and DNA Methylation on Immunity Gene Regulation and Diversification in Maize and Model Setaria viridis." The grant was awarded on September 1, 2021 with a completion date of August 31, 2024. The research is being conducted under the NSF's Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing scientific knowledge and understanding of major problems confronting the nation. Specifically, this grant will fund research exploring how transposable elements and DNA methylation impact immunity gene regulation and diversification in maize and the model grass Setaria viridis. The work is being performed in St. Paul, Minnesota.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $216.0k | 5/19/21 |