This $476,886 federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research at Boston University to develop computational models for predicting the spatiotemporal distribution of growth factors in tissue engineering scaffolds. The goal is to optimize scaffold designs to achieve optimal growth factor exposure profiles that improve tissue regeneration outcomes, particularly for cartilage repair. The research utilizes...
This federal Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research to elucidate how the fluid-like properties of tissue extracellular matrices influence cell fate decisions in response to growth factors. The $480,237 grant, awarded to The Pennsylvania State University (Penn State) on August 1, 2024, will fund the development and characterization of viscoelastic materials to study the impact of matrix viscous dissipation on cell...
This $285,570 Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) supports research at the University of Vermont & State Agricultural College (UVM) to investigate living tissues as adaptive materials. The project aims to understand how cellular adaptability influences the mechanical properties and behaviors of tissues, with potential applications in areas like wound healing, cancer, and the development of biomimetic materials.
The research will...
This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) is supporting a collaborative research effort focused on developing an intelligent lab-on-chip device to monitor and promote the maturation of stem cell-derived cardiomyocytes. The $192,150 award to the New York Institute of Technology (NYIT) aims to create an integrated system that can non-invasively evaluate cardiomyocyte maturity in real-time and adaptively apply electrical and mechanical...
This Project Grant award from the National Science Foundation (NSF) Engineering Program (CFDA 47.041) aims to develop scalable manufacturing processes for engineered extracellular vesicles (EVs) that can serve as targeted drug delivery vehicles. The $2.55M grant to Vanderbilt University, awarded on January 1, 2024, will fund research to harness cellular processes for optimizing EV production, cargo loading, and cellular uptake. The long-term goal is to establish a biomanufacturing platform...
This five-year, $397,457 Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) supports research into engineering autonomic control of cardiac tissues. The principal investigator will develop heterotypic multicellular models to measure the effects of autonomic innervation on cardiac contractile behavior and cellular composition. Stem cells will be differentiated into sympathetic and parasympathetic neurons and mixed with cardiomyocytes at different...
This four-year Project Grant from the National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems provides $480,000 to support research titled "COLLABORATIVE RESEARCH: RECODE: DIRECTING AND CONTROLLING CARDIAC DIFFERENTIATION THROUGH CELLULAR AND MICROENVIRONMENTAL MANIPULATION AND APPLICATION OF MACHINE-LEARNING." The research is being conducted under the NSF Engineering program (CFDA 47.041) to advance engineering innovation and...
This $300,000 project grant from the National Science Foundation will fund research at Cornell University from October 1, 2022 to September 30, 2025. The award is provided through NSF's Engineering Biology and Health Cluster within the Directorate for Engineering, Biological Sciences and Biotechnology, under the CFDA program for Engineering.
Specifically, researchers at Cornell University and Washington State University will work to develop new tissue engineering strategies for cartilage...
Vanderbilt University received a three-year, $298,859 Project Grant award from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering (47.041) federal grant program.
The award will support collaborative research to understand the effects of fluid flow on smooth muscle cells in an arteriole-sized microchannel. Vanderbilt University's Sponsored Programs Administration will oversee delivery of the research as the awardee institution. The...
The National Science Foundation (NSF) Division of Chemical, Bioengineering, Environmental, and Transport Systems awarded a $601,071 Project Grant to Texas A&M Engineering Experiment Station (Tees), a division of the Texas A&M University System, to conduct research under the NSF Engineering program (CFDA 47.041). The goal of this 3-year project is to develop a predictive mathematical model of the relationship between bone morphogenetic protein (BMP) signaling and stem cell...