Project Grant 2235835
Award Date
9/15/23
Completion Date
8/31/28
Dollars Obligated
$699K
Federal Agency
Division of Chemistry
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
Ann Arbor, MI 48109, USA
Similar Awards
The University of Michigan was awarded a $2.7 million Trans-NIH Research Support Project Grant from the Department of Health and Human Services National Institutes of Health Office of the Director to develop new classes of optogenetic and chemogenetic tools with feedback control. The three-year award running from August 15, 2022 to August 14, 2025 will support the design of the first closed-loop chemogenetic tool with feedback control to suppress irregularly high neuronal activity, as well as...
The National Science Foundation (NSF) awarded a $300,000 Project Grant under its Biological Sciences program (CFDA 47.074) to the Georgia TECH Research Corporation for the "TOOLS4CELLS: EAGER: A MOLECULAR PURSUIT FOR THE ENGRAM: MICROFLUIDIC TEMPORAL TRANSCRIPTOMICS FOR SINGLE CELL LEARNING" project. This 2-year effort aims to develop innovative microfluidic tools and workflows to investigate the role of non-coding RNA in learning and memory storage in single-celled organisms. Key...
The National Institutes of Health (NIH) Office of the Director awarded a $1,345,424 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) to the Regents of the University of Michigan. The grant, effective September 10, 2024 through September 9, 2027, aims to develop a novel genetically encoded "protein ticker tape" system that enables long-term, brain-wide recording of single-cell physiology in live mice without external interfacing. The technology will leverage...
This Project Grant from the National Institutes of Health's National Institute of Mental Health, under the Mental Health Research Grants program (CFDA 93.242), provides $4,819,656 to The Johns Hopkins University to develop new fluorescent protein-based kinase biosensors for multiplex neuronal imaging of signaling pathways in behaving mice. The goal is to simultaneously monitor the activity of signaling pathways involved in synaptic plasticity, such as PKA, CaMKII, ERK, and PKC, and to use in...
This Project Grant award of $360,000 from the National Science Foundation's Biological Sciences (CFDA 47.074) program aims to investigate the role of neuron-neuron communication, particularly neurotransmitter-based and neuropeptidergic chemical neurotransmission, in the post-mitotic maturation of neurons during postnatal development. The research will utilize the model organism Caenorhabditis elegans and leverage advanced genetics, behavioral assays, microscopy, and genomics tools to examine the...
The National Science Foundation (NSF) Division of Molecular and Cellular Biosciences awarded a $590,000 Project Grant to the University of California Irvine (UC Irvine) on August 15, 2023 under the Biological Sciences program (CFDA 47.074). The goal of this 3-year research project is to develop novel strategies for real-time metabolite sensing and metabolite-induced enzyme localization that can contribute to fundamental cellular knowledge and improve the efficiency of synthetic biology...
The National Science Foundation (NSF) awarded a $740,797 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to the Regents of the University of California, San Francisco (UCSF) to develop and test new methodologies for the rational design of minimalistic light-switchable single-domain proteins. The goal is to engineer these proteins to bind specifically to target proteins in only one photoswitchable chromophore state, allowing for precise spatial and temporal control...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $434,610 to the Florida Institute of Technology Inc. (Florida TECH) for the development of light-triggered molecular tools to manipulate neuronal connections and study brain function. The principal investigator, Dr. Nasri Nesnas, will collaborate with neuroscientists, including Dr. Attila Losonczy from Columbia University, to design and utilize these...
This $329,099 federal Project Grant award was provided by the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CFDA 47.070) program. The grant aims to develop new computational models to uncover the functional architecture of the brain and its role in enabling complex behaviors like navigation and decision-making. Specifically, the project will: Identify the brain systems underlying navigation in zebrafish larvae using advanced optical imaging...
The University of Chicago was awarded a $625,000 Project Grant from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences CFDA program. This three-year collaborative research project will elucidate the molecular mechanisms underlying the activation of ROBO receptor proteins that guide the growth and navigation of axons during neural circuit development. The research aims to determine how ROBO receptors have evolved to allow for the...