Project Grant 2225559
Award Date
10/1/22
Completion Date
9/30/25
Dollars Obligated
$300K
Similar Awards
This three-year, $1.2 million project grant from the National Science Foundation's Engineering program (CFDA 47.041) will support research at Washington State University and Cornell University to develop new tissue engineering strategies for cartilage regeneration. The researchers aim to stimulate adult stem cells to become mature chondrocytes for cartilage production through small molecules that interfere with bone cell differentiation genes. Real-time imaging will monitor cell growth...
This $500,000 project grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation supports research titled "GOALI/COLLABORATIVE RESEARCH: INSTABILITIES AND LOCAL STRAINS IN ENGINEERED CARTILAGE SCAFFOLD" being conducted at Cornell University from January 1, 2022 to December 31, 2024. The research aims to improve understanding of instabilities and local strains in engineered cartilage scaffolds, with the goal of enabling innovation in cartilage...
This $400,000 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to Cornell University aims to uncover the fundamental mechanistic principles of connective tissue morphogenesis and develop computational design tools to guide robotic micromanipulation for engineering architected biological tissues. The research will utilize computational models, imaging, and mechanical characterization techniques to study the influence of dynamic mechanical...
The National Science Foundation (NSF) has awarded a 5-year, $182,664 CAREER grant (CFDA 47.041 - Engineering program) to the Marshall University Research Corporation (MURC) to explore the use of electrospinning and electrospraying techniques for differentiating human adipose-derived stem cells into chondrocytes. The overarching goal is to develop an innovative and personalized approach to generate chondrocytes, or cartilage cells, that can be used for regenerative medicine applications focused...
The National Science Foundation awarded a $399,685 project grant to the University of California Irvine under the Engineering program (CFDA 47.041) to develop innovative cartilage tissue engineering strategies utilizing the microgravity environment of the International Space Station. The objectives of the three-year award beginning September 1, 2022 include employing microgravity conditions to enhance key processes in earth-based cartilage tissue engineering such as redifferentiation of expanded...
This National Science Foundation (NSF) Faculty Early Career Development (CAREER) award, under CFDA Program 47.041 Engineering, provides $624,622 to the University of Vermont & State Agricultural College to study the relationship between microscopic cartilage structure and macroscopic cartilage function under different loading conditions. The 5-year project, running from September 1, 2025 to August 31, 2030, will leverage quantitative magnetic resonance imaging (MRI) to measure cartilage...
The National Science Foundation awarded Cornell University a $663,834 project grant under the Engineering program (CFDA 47.041) for a three-year investigation of fatigue-induced damage progression in tendon from February 1, 2021 to January 31, 2024. The grant will support Cornell's Office of Sponsored Programs in conducting a multiscale study of how fatigue damage accumulates and spreads within tendons over time at micro and macro levels. The Engineering program aims to improve quality of life...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to Cornell University aims to investigate the role of acetylcholine signaling in osteocyte mechanotransduction and bone remodeling. The $612,979 award, spanning January 1, 2025 to December 31, 2027, will fund research to characterize the anatomical and functional relationship between cholinergic nerves and osteocytes in bone tissue, examine the acute effects of local acetylcholine signaling...
The National Science Foundation awarded Cornell University a three-year Project Grant totaling $430,000 under the Engineering program (CFDA 47.041) to support research titled "Mechanoregulation in the Maintenance of the Bacterial Cell Wall." From May 2021 through April 2024, Cornell researchers will investigate how bacteria sense and respond to mechanical forces during cell growth and division to maintain cell wall integrity. The Engineering program aims to improve quality of life...
The University of Rochester received a $475,811 Project Grant award from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation under the Engineering (47.041) federal grant program. The award will fund research from September 1, 2022 through August 31, 2025 to study how the accumulation of macromolecules influences cartilage mechanics and chondrocyte health. Specifically, the university will analyze how the buildup of large soluble molecules within...