This $300,000 project grant from the National Science Foundation will fund research at Cornell University from October 1, 2022 to September 30, 2025. The award is provided through NSF's Engineering Biology and Health Cluster within the Directorate for Engineering, Biological Sciences and Biotechnology, under the CFDA program for Engineering. Specifically, researchers at Cornell University and Washington State University will work to develop new tissue engineering strategies for cartilage repair....
This $500,000 project grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation supports research titled "GOALI/COLLABORATIVE RESEARCH: INSTABILITIES AND LOCAL STRAINS IN ENGINEERED CARTILAGE SCAFFOLD" being conducted at Cornell University from January 1, 2022 to December 31, 2024. The research aims to improve understanding of instabilities and local strains in engineered cartilage scaffolds, with the goal of enabling innovation in cartilage...
This $420,000 Project Grant awarded by the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports a collaborative research project at Cornell University to advance the understanding of articular cartilage, the soft tissue covering the ends of bones in joints. The research aims to investigate how cartilage responds to physical forces, particularly shear forces from twisting and sliding motions, in addition to compression. The project will integrate theoretical modeling,...
The National Science Foundation (NSF) has awarded a 5-year, $182,664 CAREER grant (CFDA 47.041 - Engineering program) to the Marshall University Research Corporation (MURC) to explore the use of electrospinning and electrospraying techniques for differentiating human adipose-derived stem cells into chondrocytes. The overarching goal is to develop an innovative and personalized approach to generate chondrocytes, or cartilage cells, that can be used for regenerative medicine applications focused...
This $230,000 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) supports a collaborative research project at the Rochester Institute of Technology (RIT) to advance the understanding of articular cartilage, the soft tissue covering the ends of bones in joints. The project will examine how cartilage responds to physical forces relevant to daily activities, integrating theoretical modeling, simulations, and experiments to study how osmotic pressure...
The National Science Foundation awarded a $399,685 project grant to the University of California Irvine under the Engineering program (CFDA 47.041) to develop innovative cartilage tissue engineering strategies utilizing the microgravity environment of the International Space Station. The objectives of the three-year award beginning September 1, 2022 include employing microgravity conditions to enhance key processes in earth-based cartilage tissue engineering such as redifferentiation of expanded...
This $1,000,000 National Science Foundation project grant will fund the Reproducible Cells and Organoids via Directed-Differentiation Encoding (RECODE) project at the University of Michigan from November 1, 2022 to October 31, 2026. The project aims to employ innovative biophysical, data-driven, and synthetic gene circuit engineering methods to better understand how adult human mesenchymal stem cells transform into chondrocytes, the cells that form cartilage. Specifically, the researchers will...
Cartilage Inc. received a $256,000 Project Grant award from the National Science Foundation Division of Industrial Innovation on February 15, 2021 to develop a biological adhesive for the fixation and integration of cartilage implants. The award is part of the Engineering program (CFDA 47.041) and will support Cartilage Inc.'s work through January 31, 2022. The Engineering program seeks to improve quality of life and economic strength through fostering innovation in engineering research and...
This $400,000 Project Grant awarded by the National Science Foundation (NSF) under CFDA Program 47.041 "Engineering" will support a collaborative research effort between Cornell University and Swiss partners to develop an integrated mechanobiology framework for engineering the shape and internal architecture of biological tissues. The key goals of the project are to: 1) use computational design tools to guide robotic micromanipulation in order to uncover the mechanical principles...
This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award supports a research project titled "CAREER: Advancing In Vivo Knowledge and Assessment of Cartilage Material Properties with Quantitative MRI" at the University of Vermont & State Agricultural College. The $624,622 award, spanning September 1, 2025 to August 31, 2030, aims to improve scientific understanding of the relationship between the microscopic structure and macroscopic function of...