The National Science Foundation (NSF) awarded a $1,300,000 project grant to the University of Kansas Center for Research Inc. from March 1, 2024 to February 29, 2028 under the NSF Biological Sciences program (CFDA 47.074). The purpose of this grant is to study how immune defense differs among closely related Drosophila species and to determine the genetic basis for these differences. The research aims to improve understanding of how species evolve to fight infections, which has implications...
This $1,220,400 Project Grant awarded by the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences supports a collaborative research project between investigators in the U.S. and U.K. to better understand the regulatory mechanisms controlling mammalian gene expression. The project, funded through NSF's Biological Sciences program (CFDA 47.074), aims to define the roles of different DNA regulatory elements and how they work together to precisely control gene expression....
This $240,000 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) funds a postdoctoral research fellowship to investigate the role of genome organization on de novo gene origination. The research aims to test a new theoretical model explaining the process of new gene evolution, by examining how the genome's structural features influence the birth of genes that arise from non-coding regions. The key components of the research include: 1)...
This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 provides funding for a postdoctoral research fellowship from July 1, 2024 to June 30, 2027. The fellowship will support research and training to investigate the rules governing interactions between genomes, environment, and phenotypes, with a focus on understanding how repetitive DNA sequences, particularly a satellite repeat on the X chromosome of Drosophila melanogaster, influence...
This National Science Foundation Project Grant award of $1,324,710 provides funding from July 1, 2022 through June 30, 2025 to support research understanding how newly evolved genes acquire protein interactions and regulatory mechanisms in Drosophila reproduction. Funded under the Biological Sciences program (CFDA 47.074), the award to the College of the Holy Cross will explore how three genes essential for Drosophila melanogaster spermatogenesis evolved novel capabilities, including physical...
This $432,173 Project Grant award was made by the National Science Foundation (NSF) under the Biological Sciences program (CFDA 47.074) to the University of Kansas Center for Research Inc. The award will support research on understanding the genetic drivers of fitness variation in wild fruit fly (Drosophila) populations. Key objectives are to: 1) Identify the genetic processes generating fitness differences among individual flies, including differences in survival, mating success, and gametic...
This $238,681 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) funds research into the genetic architecture of exploration behavior in Drosophila at the University of Houston-Downtown. The researchers will use novel arena exploration assays and integrated genetic approaches to identify genes and neurons responsible for neophilia, or attraction to novel stimuli. Specifically, they will determine dopamine signaling requirements for exploratory...
This $700,000 Project Grant awarded by the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will support research at the Van Andel Research Institute (VAI) to investigate the mechanisms of developmental plasticity and the impact of maternal metabolic state on offspring development using fruit flies as a model organism. The key objectives are to determine how maternal metabolic state alters metabolic, transcriptional, and epigenomic processes in embryos, and link...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $507,000.00 in funding to the University of California, Davis to study evolutionary and functional genomics of genetic novelties and expression adaptation in Drosophila over the period of January 10, 2025 to December 31, 2029. The key objectives of this research project are to: 1) Identify transcriptome novelties in...
This Project Grant award, provided by the National Science Foundation (CFDA 47.074 - Biological Sciences), supports research at the University of North Carolina at Chapel Hill (UNC-CH) to investigate the relationship between host immune systems and bacterial symbionts in insects, specifically aphids. The primary objective is to use transcriptome sequencing and immune assays to test the hypothesis that host immune suppression is a key mechanism explaining the distribution of symbiotic microbes...