This $400,000 National Science Foundation project grant supports research at Tufts University aimed at understanding the impact of aging on wound healing processes. Specifically, the grant funds two years of research to determine the effects of microgravity on fibroblast phenotype and wound healing response across tissue types and developmental ages. Investigators will leverage the unique environment of the International Space Station to simulate aging processes and their influence on tissue...
This $350,000 National Science Foundation project grant supports research at the University of Virginia from October 1, 2022 to September 30, 2025 under the NSF Engineering program (CFDA 47.041). The research aims to advance understanding of the effects of microgravity on wound healing processes by leveraging a sensor-integrated 3D tissue culture model. Specifically, the project will explore dynamic changes in gene and protein expression, endothelial network formation, and extracellular matrix...
This $449,582 National Science Foundation project grant funds research at Virginia Polytechnic Institute and State University from October 1, 2022 to September 30, 2025 under the NSF Engineering program (CFDA 47.041). The research aims to understand the effects of microgravity on wound healing processes by leveraging a sensor-integrated 3D tissue culture model. Specifically, the project will explore dynamic changes in gene and protein expression, structural changes in capillary network formation...
This $635,000 Project Grant awarded by the National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation supports research to understand how mechanical boundary conditions influence tissue assembly and repair in 3D fibrous microtissues. The research aims to advance knowledge about the mechanisms by which mechanical forces regulate new tissue formation and organization, particularly as it relates to wound healing. The project will integrate in vitro experiments and...
This $100,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program will support the development of an advanced wound care technology at Florida International University. Specifically, the university will create a bandage-integrated platform that provides feedback-mediated wound therapy to enable personalized care. The conformable platform is designed to non-invasively monitor multiple wound biomarkers in spatial detail and then apply targeted...
The National Institute of General Medical Sciences (NIGMS) awarded a $368,235 Project Grant (CFDA 93.859 - Biomedical Research and Research Training) to the University of New Hampshire (UNH) to establish an integrated bioengineering framework for understanding how the synergistic effects of soluble and bound factors in biomaterials influence cell signaling and modulate cell function to promote chronic wound angiogenesis and healing. The project aims to develop an in vitro microfluidic...
This $240,412 Project Grant award from the National Science Foundation (NSF) Engineering Program (CFDA 47.041) supports collaborative research at East Carolina University (ECU) to investigate how tension affects the digestion of blood clots. The research aims to test hypotheses about how inherent and applied tension on fibrin fibers impact the fibrinolysis process, which is essential for the proper dissolution of blood clots to prevent risks like strokes and heart attacks. The...
The University of California Irvine received a $422,574 project grant award from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems on February 1, 2021 with a completion date of March 31, 2023. The award supports the CAREER: TISSUE ENGINEERING BETTER CELL THERAPIES FOR WOUND HEALING project under the NSF Engineering program (CFDA 47.041). The project aims to develop advanced cell therapies for wound healing through tissue engineering...
This $250,000 National Science Foundation project grant supports the development of a microneedle-mediated adaptive phototherapy wound dressing by the University of South Florida from October 1, 2022 to November 30, 2024. The dressing integrates self-diagnosis and treatment tailored to wound conditions without external electronics or medical professionals. Microstructured microneedles act as optical waveguides to deliver localized blue or red light therapy at wound sites, changing wavelength...
This federal Project Grant award from the National Science Foundation's Division of Civil, Mechanical, and Manufacturing Innovation (CFDA 47.041 - Engineering) provides $500,000 in funding to North Carolina State University to conduct fundamental research aimed at reducing blood clotting in medical devices. The key products and services to be delivered under this award include: 1) molecular dynamics simulations and interfacial spectroscopy to understand the role of hydration layers in preventing...