Project Grant 2151127
- The National Science Foundation awarded a $548,102 project grant under the Engineering (47.041) program to the University of Texas at Austin to develop a predictive framework for understanding how bacteria sense and respond to surface mechanics upon attachment. The three-year award beginning April 1, 2022 will support research using atomic force microscopy, high-throughput culturing, finite element modeling, quantitative confocal microscopy, and genetic manipulation to characterize the stresses,...
- This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) Project Grant award of $240,000 will fund a 3-year postdoctoral fellowship to research the adaptive response of bacteria to bacteriophage infection and high hydrostatic pressure. The fellow will develop novel fluorescence microscopy techniques to quantify bacterial growth, cell size, and morphology under these environmental stressors using model organisms E. coli, P. aeruginosa, and S. piezotolerans. The project...
- This National Science Foundation project grant of $512,676 will fund research at Duke University from August 2022 to July 2025 under the Biological Sciences program (CFDA 47.074). The research aims to advance understanding of mechanosensitive channels in bacteria through single-molecule force spectroscopy experiments using an atomic force microscope. Investigators will observe the opening of individual mechanosensitive channels in living E. coli and B. subtilis bacteria in response to mechanical...
- Federal Project Grant Award Summary The University of Rhode Island Research Office received an $801,000 Project Grant from the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074) effective August 1, 2025, through July 31, 2028. This award supports fundamental research investigating toxin activation mechanisms within bacterial toxin-antitoxin (TA) systems, specifically examining how protein quality control factors...
- This $100,000 Project Grant award from the National Science Foundation (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research to develop new theory and predictive models for understanding how environmental pressures shape the evolution of virulence in opportunistic bacterial pathogens. The project aims to: (I) Develop and test predictive models of strain-specific virulence, transmission, and environmental origins for the model pathogen Pseudomonas aeruginosa; and (II)...
- This two-year National Science Foundation project grant of $138,000 supports research into the evolution of bacterial strategies for evading predation by amoebae. The grant was awarded on July 1, 2021 to the University of Missouri-St. Louis under the Biological Sciences program (CFDA 47.074) administered by NSF's Division of Biological Infrastructure. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the national scientific enterprise through...
- The National Science Foundation Division of Molecular and Cellular Biosciences awarded a $288,550 Project Grant to the University of Rhode Island for research titled "EAGER: MECHANISM OF TOXIN ACTIVATION AND FUNCTION IN BACTERIA." The two-year award running from July 1, 2021 to June 30, 2023 is being conducted under the Biological Sciences program (CFDA 47.074). This grant aims to advance understanding of major problems confronting the nation by supporting basic research into the...
- This National Science Foundation (NSF) Project Grant under the CFDA program "Biological Sciences" (47.074) is awarded to Trustees of Boston University to develop and optimize optogenetic tools for selecting bacterial cells based on dynamic, time-varying traits. The $796,158 award, effective August 1, 2023 through July 31, 2026, supports the researchers in creating light-inducible genetic constructs that trigger antibiotic resistance, enabling the isolation of bacteria exhibiting...
- The University of Chicago received a $358,830 Project Grant award from the National Science Foundation (NSF) Division of Integrative Organismal Systems under the Biological Sciences program (CFDA 47.074), effective September 1, 2025 through August 31, 2028. This award supports fundamental research investigating the evolution and mechanisms of thermotolerance in cyanobacteria, with the primary deliverables including scientific data on genomic features that predict optimal growth temperature,...
- This National Science Foundation (NSF) Biological Sciences project grant, awarded under CFDA 47.074, provides $242,000 to the University of Houston System to study the phenotypic plasticity and adaptive evolution of a freshwater microbial eukaryote in response to environmental changes caused by road salts and nanoparticle biocides. The 3-year project will measure organismal and gene expression traits before and after experimental evolution in contaminated environments to understand how...
The National Science Foundation awarded a $800,000 Project Grant to The University of Toledo to support research characterizing the stress response mechanisms of Vibrio bacteria through January 2025. Funded under the Biological Sciences program (CFDA 47.074), this award will further the program's goals of advancing biological science knowledge and understanding major challenges. Specifically, the University of Toledo researchers will characterize the Vibrio cholerae SIPA pathway and its role in bacterial survival under stressors like antimicrobial peptides. They will investigate regulation of the SIPA stress response system and how it integrates with other biological processes in V. cholerae. Researchers will also study stress response mechanisms in other environmental Vibrio species of ecological importance. The award additionally supports science education activities involving graduate students and local high school teachers and students. Findings from this research could improve understanding of stress responses linked to biofilm formation, virulence, antibiotic tolerance in pathogenic bacteria.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $800.0k | 1/28/22 |