Project Grant 2145004
- The National Science Foundation awarded Cornell University a $663,834 project grant under the Engineering program (CFDA 47.041) for a three-year investigation of fatigue-induced damage progression in tendon from February 1, 2021 to January 31, 2024. The grant will support Cornell's Office of Sponsored Programs in conducting a multiscale study of how fatigue damage accumulates and spreads within tendons over time at micro and macro levels. The Engineering program aims to improve quality of life...
- The National Science Foundation awarded a $750,000 Project Grant to Rutgers, The State University under the Engineering program (CFDA 47.041) from September 1, 2022 to August 31, 2025. The grant funds research to develop an injectable nanoparticle therapy to restore strength and length to damaged tendons and ligaments. Specifically, the university will investigate combining a thermosensitive polymer and crosslinking agent to stabilize joints by quickly strengthening and returning tissues like...
- This $300,000 project grant from the National Science Foundation will fund research at Cornell University from October 1, 2022 to September 30, 2025. The award is provided through NSF's Engineering Biology and Health Cluster within the Directorate for Engineering, Biological Sciences and Biotechnology, under the CFDA program for Engineering. Specifically, researchers at Cornell University and Washington State University will work to develop new tissue engineering strategies for cartilage repair....
- This $500,000 project grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation supports research titled "GOALI/COLLABORATIVE RESEARCH: INSTABILITIES AND LOCAL STRAINS IN ENGINEERED CARTILAGE SCAFFOLD" being conducted at Cornell University from January 1, 2022 to December 31, 2024. The research aims to improve understanding of instabilities and local strains in engineered cartilage scaffolds, with the goal of enabling innovation in cartilage...
- This federal Project Grant award for $160,000.00, provided by the National Science Foundation (NSF) Office of Integrative Activities (CFDA 47.083), supports collaborative research at Boise State University to develop data-driven mechanomics capabilities for uncovering age-related mechanoregulation of bone and musculoskeletal tissues. The research aims to quantify the mechanical forces within living cells and determine how changes to these forces impact cellular protein production and...
- This National Science Foundation (NSF) Engineering Research Initiation (ERI) grant, award number 2347433, provides $200,000 in funding to Lafayette College to conduct fundamental research on the mechanical properties of ligaments and tendons. The goal is to better understand how these musculoskeletal tissues deform and fail by examining the mechanical behavior of the interfascicular matrix and fascicles that make up the tissue structure. The research team will use stereo digital image...
- This three-year, $1.2 million project grant from the National Science Foundation's Engineering program (CFDA 47.041) will support research at Washington State University and Cornell University to develop new tissue engineering strategies for cartilage regeneration. The researchers aim to stimulate adult stem cells to become mature chondrocytes for cartilage production through small molecules that interfere with bone cell differentiation genes. Real-time imaging will monitor cell growth...
- This $360,580 Project Grant award from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846), supports research to develop an engineered extracellular matrix (EECM) that can promote regenerative healing in tendons. The University of Oregon will fabricate anisotropic PEG hydrogel-based EECM scaffolds and evaluate their ability to guide the alignment and matrix deposition of human...
- This Project Grant award of $285,630 from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) will support research at the University of New England (UNE) to elucidate the molecular mechanisms by which articular chondrocytes (cartilage cells) respond to mechanical forces and regulate cartilage health. The goal is to advance the understanding of the pathogenesis of osteoarthritis, a leading cause of joint pain and disability. The research objectives include establishing...
- This Project Grant award for $285,570.00 was provided by the National Science Foundation (NSF) Office of Integrative Activities under CFDA 47.083. The award supports a 5-year research project titled "TISSUES AS ADAPTIVE MATERIALS: INVESTIGATING THE ROLE OF CELLULAR ADAPTABILITY IN TISSUE MECHANICS" at the University of Vermont. This research investigates how the adaptive properties of living cells, such as their ability to change structure and coordinate movements in response to...
The Regents of the University of Idaho received a three-year, $231,873 Project Grant from the National Science Foundation Division of Civil, Mechanical, and Manufacturing Innovation to understand regulators of collagen crosslinking enzymes for tendon formation. Funded under the NSF's Engineering program (CFDA 47.041), the research aims to define the mechanisms that control collagen crosslinking enzyme production by tendon and stem cells. Investigators will evaluate adult stem cells and tendon cells isolated from developing rat tendons under mechanical stimuli using a bioreactor and biochemical growth factors. Outcomes seek to advance knowledge of how collagen crosslinking is regulated to contribute to tendon formation understanding and potential injury treatment therapies. The award also supports undergraduate research experiences, graduate fellowship applications, and outreach aligned with the NSF's statutory mission to stimulate competitive engineering research and education.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $231.9k | 5/3/22 |