This National Science Foundation (NSF) Division of Civil, Mechanical, and Manufacturing Innovation award provides $199,824 to Western Carolina University from January 1, 2024 to December 31, 2025 to conduct fundamental research on how stress-induced histomorphogenesis affects long-term leaching from implanted medical devices using phase field models. The research aims to develop computer simulations that can more accurately capture the impact of tissue changes near implanted devices on...
The National Science Foundation awarded a $413,702 project grant to Worcester Polytechnic Institute under the Engineering program (CFDA 47.041) for research titled "CAREER: MIXING AND VORTICITY DYNAMICS IN ACTIVE FLUID SYSTEMS" from July 1, 2021 to June 30, 2026. The grant will support research exploring mixing and vorticity dynamics in active fluid systems, advancing the NSF Directorate for Engineering's goal of improving quality of life and economic strength through innovative...
This Project Grant award, with a total funding amount of $265,151.00, was provided by the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to the University of Southern California. The project aims to use mathematical modeling and experiments to understand what regulates leakiness in the lymphatic system, with the goal of developing strategies to modulate lymphatic permeability. The research will investigate how lipids regulate CD36, a long-chain fatty acid translocase,...
This $333,567 federal Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) will fund a collaborative research effort at Saint Louis University to determine the role of lipids in regulating lymphatic permeability. The project aims to develop an integrated computational and experimental approach to understand how lipids and the CD36 translocase regulate lymphatic vessel integrity and cell signaling. Researchers will use a systems biology methodology...
This National Science Foundation (NSF) Engineering Program (CFDA 47.041) award of $470,955 to Cornell University aims to develop a microfluidic cell culture platform to study breast cancer-associated secondary lymphedema. The 5-year project seeks to comprehend the regulation of lymphatic structure and function in breast cancer, and discover new treatment approaches for the over 150 million lymphedema patients worldwide. The research involves creating engineered lymphatic vessel models to analyze...
This National Science Foundation (NSF) Project Grant award, provided under the NSF Engineering program (CFDA 47.041), supports research to study the coordination and force transmission of beating cilia. The $284,857 award, granted on March 1, 2025, will fund a project led by The Washington University in St. Louis to investigate how coordination of cilia, which are slender structures that move fluid in the human body and single-celled organisms, is maintained and affected by changes in fluid...
This $314,769 Project Grant awarded by the National Science Foundation's Engineering program (CFDA 47.041) supports research that aims to advance the fundamental understanding of how cells and tissues communicate information about their mechanical environment. The award, effective from February 1, 2025 to January 31, 2030, will fund the development of new material platforms based on magnetic materials that can dynamically change local stiffness via magnetic fields. Experiments will explore how...
This National Science Foundation Project Grant of $419,750 will fund research at Washington University in St. Louis from August 1, 2022 to July 31, 2025 to study how living cells move across dissimilar physical environments and retain mechanical memories of prior environments. Specifically, the award will integrate experiments and computational modeling to examine how forces generated by cells modify their surroundings in two mechanically different environments during migration. This will reveal...
The National Science Foundation awarded a $890,510 project grant to Virginia Commonwealth University under the Engineering federal grant program (CFDA 47.041) for research titled "BIOMECHANICS OF LEADER CELLS." The five-year award, issued February 1, 2022 with a completion date of January 31, 2027, will support research into the biomechanics of leader cells. The NSF's Engineering program seeks to improve quality of life and economic strength by fostering innovation and excellence in...
This National Science Foundation (NSF) Project Grant award, under the Engineering program (CFDA 47.041), provides $283,237 to North Carolina State University (NC State) to conduct fundamental research on how ultra-soft inclusions, such as cells and cell-like particles, interact with fiber networks and affect the overall deformation behavior of the host material. The goal is to gain new insights into the design and fabrication of bio-inspired, adaptive materials for applications in smart...