This Project Grant award from the National Science Foundation (NSF) Engineering program (CFDA 47.041) provides $284,857 to The Washington University in St. Louis to support research on the coordination and force transmission of beating cilia. The 3-year project, running from March 2025 to February 2028, will study how coordination of cilia movement is maintained in the single-celled organism Tetrahymena. Specifically, the research will measure deformations of basal bodies, quantify metachronal coordination of cilia, and develop computational models to clarify the role of intracellular force transmission in cilia coordination. This work aims to help understand and potentially treat diseases related to cilia defects, as well as inform the design of man-made systems to move fluid or propel objects using coordinated wave generators. The project will also support workforce development through research, education, and outreach activities involving graduate students, undergraduates, and K-12 students.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $284.9k | 3/12/25 |