Project Grant 2134603
- This Project Grant from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $2,396,627 to Purdue University from January 1, 2022 through December 31, 2026. The grant supports research titled "MIM: Microbial Division of Labor in Polysaccharide-Degrading Communities." Purdue University will investigate how microbial communities divide labor to degrade complex plant polysaccharides. Baylor University, Washington State University, the University of...
- Federal Grant Award Summary This $347,628 CAREER (Faculty Early Career Development) Project Grant, awarded by the National Science Foundation's Division of Molecular and Cellular Biosciences under the Biological Sciences program (CFDA 47.074), commenced June 1, 2025, and extends through May 31, 2030. The award supports fundamental research conducted at Purdue University to elucidate the assembly, supramolecular organization, and functional mechanisms of bacterial microcompartments—specialized...
- This National Science Foundation Office of Emerging Frontiers and Multidisciplinary Activities Project Grant award, titled "EFRI ELIS: BIOSYNTHETIC ADDITIVE MANUFACTURING OF LIVING BUILDING MATERIALS", provides $1,999,999.00 in funding over the period of September 1, 2023 to August 31, 2027. The award aims to integrate advanced manufacturing, synthetic biology, and materials science to transform microbe-engineered lignocellulosic biomass into a printable ink for biosynthetic additive...
- The National Science Foundation Office of Emerging Frontiers and Multidisciplinary Activities awarded a $2 million Project Grant under the Engineering (47.041) federal grant program to The Trustees of the University of Pennsylvania. The four-year award beginning September 2021 will support research into Distributed Ribonucleic Acid (RNA) Manufacturing via Continuous Enzymatic Reaction and Separation in Biphasic Liquid Media. Sub-awards were provided to the University of Oklahoma, University of...
- The National Science Foundation (NSF) awarded a $274,980 SBIR Phase I Project Grant to Cisterna Biologics, Inc. to develop a novel platform for cost-efficient mRNA production in yeast. The project aims to transform yeast cells into efficient mRNA factories and utilize advanced chromatographic techniques for purification, with the goal of reducing mRNA manufacturing costs by 90% compared to current in vitro transcription methods. Key technical objectives include demonstrating stable mRNA fusion...
- The National Science Foundation (NSF) awarded a $1,199,997 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of Colorado-Denver. The grant will fund research to improve understanding of the mechanisms underlying messenger RNA (mRNA) localization and translation, and develop machine learning models to better predict protein production from mRNA. The project will apply recent advancements in RNA sequencing technology to study how factors like tRNA abundance and...
- This federal Project Grant award of $820,000 from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) supports research conducted by the University of Delaware to control the spatial arrangement and function of synthetic microbial communities. The key products and services to be delivered under this 3-year award include: Repurposing innovative biological containment tools to direct the self-assembly of specific microbes within a larger synthetic microbial community....
- This Project Grant from the National Science Foundation's Division of Chemical, Bioengineering, Environmental, and Transport Systems provides $500,000 to the Regents of the University of California at Riverside for research on rapid biomanufacturing of mRNA vaccines in plant chloroplasts. The award period is from January 1, 2022 to December 31, 2023. The research is funded under the NSF Directorate for Engineering's 47.041 CFDA program, which aims to improve quality of life and economic strength...
- Federal Project Grant Award Summary Purdue University received a $501,917 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2030. This five-year research initiative focuses on elucidating the molecular mechanisms of CRISPR-associated transposons (CASTs) and RNA-guided transcriptional regulation systems. The research employs single-particle...
- The National Science Foundation awarded Purdue University a $262,312 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) for work spanning August 1, 2021 through July 31, 2023. The grant funds collaborative research titled "COLLABORATIVE RESEARCH: MSA: UNCOVERING LOCAL AND REGIONAL CONTROLS ON ORGANIC MATTER PROCESSING IN FRESHWATERS USING IN SITU OPTICAL SENSORS." The Biological Sciences program supports basic research to increase scientific knowledge and...
This two-year, $512,200 Project Grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports the development of a microbial "foundry" for distributed manufacturing of mRNA-containing biomaterials. Awarded on September 1, 2021 to Purdue University with a completion date of August 31, 2023, the grant will further the program's goals of advancing the biological sciences and strengthening the national scientific enterprise. Under this award, Purdue University will establish capabilities for engineering microbes to produce mRNA-containing materials at remote locations. The university will also provide $50,000 in sub-award funding to the University of Delaware to support related work developing mRNA-based biomaterials. Once established, this microbial foundry is intended to enable more distributed and scalable production of mRNA materials for applications in biomedicine and biomanufacturing.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $12.2k | 7/15/22 | ||
| Not listed | $500.0k | 8/13/21 |